TY - JOUR
T1 - 10'-Chloro-3′,4′-dihydro-2′H-spiro[cyclopropane-1, 7'(6′H)-pyrimido[2,1-a]isoquinolin]-6′-one
AU - Okuda, Kensuke
AU - Hirota, Takashi
AU - Nishina, Yuta
AU - Ishida, Hiroyuki
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012/11
Y1 - 2012/11
N2 - In the title compound, C14FH13ClN2O, the fused hydropyrimidine ring adopts an envelope conformation with one of the methylene C atoms at the flap. The three-membered ring is approximately perpendicular to the attached isoquinoline ring system, with a dihedral angle of 89.44(11)°. In the crystal, molecules are linked by a weak C-H⋯π interaction, forming a helical chain along the c axis.
AB - In the title compound, C14FH13ClN2O, the fused hydropyrimidine ring adopts an envelope conformation with one of the methylene C atoms at the flap. The three-membered ring is approximately perpendicular to the attached isoquinoline ring system, with a dihedral angle of 89.44(11)°. In the crystal, molecules are linked by a weak C-H⋯π interaction, forming a helical chain along the c axis.
KW - R factor = 0.031
KW - T = 180 K
KW - data-to-parameter ratio = 20.6
KW - mean ̄(C-C) = 0.002 Å
KW - single-crystal X-ray study
KW - wR factor = 0.079
UR - http://www.scopus.com/inward/record.url?scp=84870894778&partnerID=8YFLogxK
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U2 - 10.1107/S1600536812044261
DO - 10.1107/S1600536812044261
M3 - Article
C2 - 23284549
AN - SCOPUS:84870894778
SN - 1600-5368
VL - 68
SP - o3252
JO - Acta Crystallographica Section E: Structure Reports Online
JF - Acta Crystallographica Section E: Structure Reports Online
IS - 11
ER -