12T061C, a new Julichrome family radical scavenger from Streptomyces species

Toshikazu Komoda, Naoko Saeki, Yoshitaka Koseki, Hiromasa Kiyota

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


The new radical scavenger 12T061C (C20H22O7) has been identified from a culture of Streptomyces species. Spectroscopic elucidation showed that this compound is a new Julichrome family compound. 12T061C shows a potent radical-scavenging activity with an ED50 of 18 μm that is similar to those of the known antioxidant compounds α-tocopherol (ED50 16 μm) and quercetin (ED50 3 μm).

Original languageEnglish
Pages (from-to)271-274
Number of pages4
JournalHeterocyclic Communications
Issue number5
Publication statusPublished - Oct 1 2014


  • 2 2-diphenyl-1-picrylhydrazyl (DPPH)
  • Julichrome
  • Streptomyces species
  • radical scavenger

ASJC Scopus subject areas

  • Organic Chemistry


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