A case of alpha-fetoprotein-producing minute mucosal gastric cancer

Shoji Hirasaki, Junro Kataoka, Junichirou Nasu, Minoru Matsubara, Fusao Ikeda, Seiyuu Suzuki

Research output: Contribution to journalArticlepeer-review


The endoscopic examination of a 63-year-old man revealed a IIc lesion, 5mm in diameter, in the lesser curvature of the gastric body. His serum alpha-fetoprotein (AFP) level was high at 14.3ng/ml. Immunohistological studies on the biopsy specimens showed a positive reaction for AFP. Endoscopic ultrasonography revealed that the tumor was limited to the second layer of the gastric wall and this tumor was diagnosed as mucosal cancer. The final diagnosis was AFP-producing mucosal gastric cancer (AFPMGC). Cases of AFPMGC are rarely encountered. The present case suggested that even minute mucosal gastric cancer could produce AFP.

Original languageEnglish
Pages (from-to)1051-1056
Number of pages6
JournalJapanese Journal of Gastroenterology
Issue number7
Publication statusPublished - Jul 2007

ASJC Scopus subject areas

  • Gastroenterology


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