A case of diffuse esophageal spasm treated with peroral endoscopic myotomy

Yuusaku Sugihara, Keita Harada, Ryo Kato, Kenji Yamauchi, Hiroyuki Sakae, Seiji Kawano, Sakiko Hiraoka, Yoshiro Kawahara, Fumio Otsuka, Hiroyuki Okada

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The indications for peroral endoscopic myotomy (POEM) have been expanded to include diffuse esophageal spasm (DES). A 67-year-old Japanese man presented with a 4-year history of dysphagia. Endoscopy and upper gastrography revealed abnormal peristaltic movements involving interruption of normal peristalsis, and a diverticulum located at the 2 o'clock esophageal position. High-resolution manometry indicated DES. POEM with a long (15 cm) myotomy was performed for the abnormal contractions, which subsequently disappeared along with dysphagia improvement. Our results suggest that esophageal motility disorders accompanying a diverticulum may be eliminated by POEM without treating the diverticulum itself. We speculate that POEM ameliorates esophageal diverticulum by reducing internal esophageal pressure.

Original languageEnglish
Pages (from-to)595-600
Number of pages6
JournalActa medica Okayama
Issue number6
Publication statusPublished - 2018


  • Diffuse esophageal spasm (DES)
  • Diverticulum
  • High-resolution manometry (HRM)
  • Peroral endoscopic myotomy (POEM)

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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