A case of early extrahepatic bile duct cancer showing diffuse growth

Seiyuu Suzuki, Shoji Hirasaki, Eiichiro Yumoto, Hiromichi Yamane, Hideaki Taniguchi, Fusao Ikeda, Minoru Matsubara

Research output: Contribution to journalArticlepeer-review


A 74-year-old woman visited our hospital for a health checkup, and liver dysfunction and cholangiectasis were detected. Further examinations revealed a protruding lesion spreading diffusely from the upper to the lower extra-hepatic bile duct. On a diagnosis of extra-hepatic bile duct cancer, the patient underwent pancreato-duodenectomy with preservation of the pyloric ring. Small papillary denticulate lesions, forming papillary adenocarcinoma, was scattered over a flat granular lesion of atypical hyperplasia. This morphological pattern is rare, and suggests that the cancer cells may have derived from atypical hyperplastic epithelium.

Original languageEnglish
Pages (from-to)703-708
Number of pages6
JournalJapanese Journal of Gastroenterology
Issue number5
Publication statusPublished - May 1 2007

ASJC Scopus subject areas

  • Gastroenterology


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