A case of focal bone marrow reconversion mimicking bone metastasis: The value of 111Indium chloride

Takashi Tanaka; Hideo Gobara; Ryota Inai; Toshihiro Iguchi; Akihiro Tada; Shuhei Sato; Hiroyuki Yanai; Susumu Kanazawa

A case of focal bone marrow reconversion mimicking bone metastasis: The value of ¹¹¹Indium chloride

Takashi Tanaka, Hideo Gobara, Ryota Inai, Toshihiro Iguchi, Akihiro Tada, Shuhei Sato, Hiroyuki Yanai, Susumu Kanazawa

Research output: Contribution to journal › Article › peer-review

Abstract

We present a case of a 66-year-old man with esophageal carcinoma. ¹⁸Fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) for evaluating distant metastasis and staging revealed ¹⁸F-FDG uptake in the third lumbar vertebra and other vertebrae. Magnetic resonance imaging could not differentiate bone metastases from benign bone lesions. We considered the possibility of bone marrow reconversion. ¹¹¹Indium chloride (¹¹¹In-Cl₃) scintigraphy with single-photon emission computed tomography/computed tomography (SPECT/CT) revealed erythroid bone marrow components in the bone lesions. The diagnosis of bone marrow reconversion was pathologically confirmed by a bone biopsy of the third lumbar vertebra. The patient underwent esophagectomy and has remained disease-free in the 2 years since. To the best of our knowledge, this is the first report to describe the usefulness of ¹¹¹In-Cl₃ with SPECT/CT for the diagnosis of bone marrow reconversion.

Original language	English
Pages (from-to)	285-290
Number of pages	6
Journal	Acta medica Okayama
Volume	70
Issue number	4
Publication status	Published - 2016

Keywords

Bone marrow reconversion
Bone metastasis
F-FDG PET/CT
Indium chloride scintigraphy
SPECT/CT

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

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title = "A case of focal bone marrow reconversion mimicking bone metastasis: The value of 111Indium chloride",

abstract = "We present a case of a 66-year-old man with esophageal carcinoma. 18Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for evaluating distant metastasis and staging revealed 18F-FDG uptake in the third lumbar vertebra and other vertebrae. Magnetic resonance imaging could not differentiate bone metastases from benign bone lesions. We considered the possibility of bone marrow reconversion. 111Indium chloride (111In-Cl3) scintigraphy with single-photon emission computed tomography/computed tomography (SPECT/CT) revealed erythroid bone marrow components in the bone lesions. The diagnosis of bone marrow reconversion was pathologically confirmed by a bone biopsy of the third lumbar vertebra. The patient underwent esophagectomy and has remained disease-free in the 2 years since. To the best of our knowledge, this is the first report to describe the usefulness of 111In-Cl3 with SPECT/CT for the diagnosis of bone marrow reconversion.",

keywords = "Bone marrow reconversion, Bone metastasis, F-FDG PET/CT, Indium chloride scintigraphy, SPECT/CT",

author = "Takashi Tanaka and Hideo Gobara and Ryota Inai and Toshihiro Iguchi and Akihiro Tada and Shuhei Sato and Hiroyuki Yanai and Susumu Kanazawa",

year = "2016",

language = "English",

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journal = "Acta Medica Okayama",

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T1 - A case of focal bone marrow reconversion mimicking bone metastasis

T2 - The value of 111Indium chloride

AU - Tanaka, Takashi

AU - Gobara, Hideo

AU - Inai, Ryota

AU - Iguchi, Toshihiro

AU - Tada, Akihiro

AU - Sato, Shuhei

AU - Yanai, Hiroyuki

AU - Kanazawa, Susumu

PY - 2016

Y1 - 2016

N2 - We present a case of a 66-year-old man with esophageal carcinoma. 18Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for evaluating distant metastasis and staging revealed 18F-FDG uptake in the third lumbar vertebra and other vertebrae. Magnetic resonance imaging could not differentiate bone metastases from benign bone lesions. We considered the possibility of bone marrow reconversion. 111Indium chloride (111In-Cl3) scintigraphy with single-photon emission computed tomography/computed tomography (SPECT/CT) revealed erythroid bone marrow components in the bone lesions. The diagnosis of bone marrow reconversion was pathologically confirmed by a bone biopsy of the third lumbar vertebra. The patient underwent esophagectomy and has remained disease-free in the 2 years since. To the best of our knowledge, this is the first report to describe the usefulness of 111In-Cl3 with SPECT/CT for the diagnosis of bone marrow reconversion.

AB - We present a case of a 66-year-old man with esophageal carcinoma. 18Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for evaluating distant metastasis and staging revealed 18F-FDG uptake in the third lumbar vertebra and other vertebrae. Magnetic resonance imaging could not differentiate bone metastases from benign bone lesions. We considered the possibility of bone marrow reconversion. 111Indium chloride (111In-Cl3) scintigraphy with single-photon emission computed tomography/computed tomography (SPECT/CT) revealed erythroid bone marrow components in the bone lesions. The diagnosis of bone marrow reconversion was pathologically confirmed by a bone biopsy of the third lumbar vertebra. The patient underwent esophagectomy and has remained disease-free in the 2 years since. To the best of our knowledge, this is the first report to describe the usefulness of 111In-Cl3 with SPECT/CT for the diagnosis of bone marrow reconversion.

KW - Bone marrow reconversion

KW - Bone metastasis

KW - F-FDG PET/CT

KW - Indium chloride scintigraphy

KW - SPECT/CT

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SN - 0386-300X

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JO - Acta Medica Okayama

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IS - 4

ER -

A case of focal bone marrow reconversion mimicking bone metastasis: The value of ¹¹¹Indium chloride

Abstract

Keywords

ASJC Scopus subject areas

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