TY - JOUR
T1 - A case of focal nodular hyperplasia with hepatic failure treated with liver transplantation
AU - Yasunaka, Tetsuya
AU - Takeuchi, Yasuto
AU - Takaki, Akinobu
AU - Kondo, Fukuo
AU - Yoshizumi, Tomoharu
AU - Kohashi, Kenichi
AU - Oyama, Atsushi
AU - Adachi, Takuya
AU - Wada, Nozomu
AU - Onishi, Hideki
AU - Shiraha, Hidenori
AU - Okada, Hiroyuki
N1 - Publisher Copyright:
© 2021, Japanese Society of Gastroenterology.
PY - 2021
Y1 - 2021
N2 - Focal nodular hyperplasia (FNH) is a benign nodular lesion, but because of its feature of portal tract vessel abnormality, it may induce portal hypertension. A 27-year-old woman was admitted with a fever. A large nodule with satellite lesions was found in the liver and cotton wool-like feature of arteries were detected on angiography. Technetium galactosyl serum albumin scintigraphy and diagnostic laparoscopy showed that the tumor site was functional, while the surrounding area was a non-functional fibrotic area. A biopsy specimen indicated that the nodular lesion was an FNH-like lesion. She experienced several instances of variceal rupture and suffered liver failure, receiving liver transplantation. The excised liver showed a centrally scarred area in the nodule, indicating that the diagnosis was FNH. We herein report this case as a rare case of FNH that progressed to liver failure.
AB - Focal nodular hyperplasia (FNH) is a benign nodular lesion, but because of its feature of portal tract vessel abnormality, it may induce portal hypertension. A 27-year-old woman was admitted with a fever. A large nodule with satellite lesions was found in the liver and cotton wool-like feature of arteries were detected on angiography. Technetium galactosyl serum albumin scintigraphy and diagnostic laparoscopy showed that the tumor site was functional, while the surrounding area was a non-functional fibrotic area. A biopsy specimen indicated that the nodular lesion was an FNH-like lesion. She experienced several instances of variceal rupture and suffered liver failure, receiving liver transplantation. The excised liver showed a centrally scarred area in the nodule, indicating that the diagnosis was FNH. We herein report this case as a rare case of FNH that progressed to liver failure.
KW - Focal nodular hyperplasia-like lesion
KW - Hepatic failure
KW - Liver transplantation
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U2 - 10.1007/s12328-021-01529-w
DO - 10.1007/s12328-021-01529-w
M3 - Article
C2 - 34807397
AN - SCOPUS:85119669772
SN - 1865-7257
JO - Clinical Journal of Gastroenterology
JF - Clinical Journal of Gastroenterology
ER -