A case of hepatic angiomyolipoma difficult to distinguish from hepatocellular carcinoma

Masahiro Takahara, Yasuhiro Miyake, Kazuyuki Matsumoto, Daisuke Kawai, Eisuke Kaji, Tatsuya Toyokawa, Mohirito Nakatsu, Masaharu Ando, Mamoro Hirohata

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


We report a case of hepatic angiomyolipoma with uncommon clinical features. A 56-year-old man presented with a hepatic tumor in the caudate lobe. The tumor was hypoechoic on ultrasonography, showed early-phase hyperattenuation on enhanced computed tomography and did not absorb iron on superparamagnetic iron oxide-enhanced magnetic resonance imaging. Hepatocellular carcinoma was highly suspected, and the patient underwent hepatic resection. Histologically, the tumor was mainly composed of smooth muscle cells and contained small amounts of adipose cells and blood vessels. On immunohistochemical staining, the smooth muscle cells were positive for a melanocytic cell-specific monoclonal antibody. In cases with uncommon features of angiomyolipoma, it is quite difficult to distinguish angiomyolipoma from hepatocellular carcinoma.

Original languageEnglish
Pages (from-to)2930-2932
Number of pages3
JournalWorld journal of gastroenterology
Issue number23
Publication statusPublished - Jun 21 2009
Externally publishedYes


  • Adipose cell
  • HMB-45
  • Hepatic angiomyolipoma
  • Hepatocellular carcinoma
  • Smooth muscle cell

ASJC Scopus subject areas

  • Gastroenterology


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