A case of mediastinal granular cell tumor with horner’s syndrome

Yoshinobu Shikatani, Mikio Okazaki, Nobuhiko Sakao, Shungo Yukumi, Hisayuki Shigematsu, Sohei Kitazawa, Yoshifumi Sano

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Granular cell tumor (GCT) is found in various organs but is rare in the mediastinum. We report a case of mediastinal GCT in a 19-year-old woman who presented with left ptosis and miosis. CT and MRI revealed a 29-mm well-circumscribed tumor located close to the first thoracic vertebra with features suggesting a neurogenic tumor. The tumor was completely excised using single-port video-assisted thoracoscopic surgery. Histopathological and immu­nohistochemical analysis revealed that the tumor was a benign GCT. Postoperatively, left ptosis and miosis had improved slightly. To our knowledge, this is the first report regarding mediastinal GCT presenting with preoperative Horner’s syndrome.

Original languageEnglish
Pages (from-to)567-569
Number of pages3
JournalAnnals of Thoracic and Cardiovascular Surgery
Issue number6
Publication statusPublished - Dec 20 2015
Externally publishedYes


  • Granular cell tumor
  • Horner’s syndrome
  • Mediastinal tumor

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Gastroenterology


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