A Case of Nephrotic Syndrome and Renal Dysfunction in a Pregnant Woman with Diabetes Mellitus

K. Hironaka; H. Makino; I. Kumagai; T. Haramoto; Y. Yamasaki; K. Shikata; M. Takahashi; M. Nishii; Z. Ota

doi:10.1111/j.1464-5491.1992.tb01785.x

A Case of Nephrotic Syndrome and Renal Dysfunction in a Pregnant Woman with Diabetes Mellitus

K. Hironaka, H. Makino, I. Kumagai, T. Haramoto, Y. Yamasaki, K. Shikata, M. Takahashi, M. Nishii, Z. Ota

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A 29‐year‐old diabetic woman who developed severe anaemia, nephrotic syndrome, and hypertension before the 28th week of gestation, had residual evidence of toxaemia and renal dysfunction more than 1 month following delivery. The histopathological findings of renal biopsy specimens were considered most consistent with toxaemia of pregnancy complicated by diabetic glomerulosclerosis. We consider that rapid acceleration of renal dysfunction may have been induced by: (1) poor control of diabetes before pregnancy; (2) glomerular hyperfiltration of the remnant nephrons throughout pregnancy; (3) hypercoagulopathy associated with pregnancy; (4) appearance of hypertension following these three conditions. 1992 Diabetes UK

Original language	English
Pages (from-to)	307-311
Number of pages	5
Journal	Diabetic Medicine
Volume	9
Issue number	3
DOIs	https://doi.org/10.1111/j.1464-5491.1992.tb01785.x
Publication status	Published - Apr 1992

Keywords

Diabetic glomerulosclerosis
Glomerular hyperfiltration
Hypercoagulopathy
Toxaemia of pregnancy

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1464-5491.1992.tb01785.x

Cite this

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abstract = "A 29‐year‐old diabetic woman who developed severe anaemia, nephrotic syndrome, and hypertension before the 28th week of gestation, had residual evidence of toxaemia and renal dysfunction more than 1 month following delivery. The histopathological findings of renal biopsy specimens were considered most consistent with toxaemia of pregnancy complicated by diabetic glomerulosclerosis. We consider that rapid acceleration of renal dysfunction may have been induced by: (1) poor control of diabetes before pregnancy; (2) glomerular hyperfiltration of the remnant nephrons throughout pregnancy; (3) hypercoagulopathy associated with pregnancy; (4) appearance of hypertension following these three conditions. 1992 Diabetes UK",

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AU - Hironaka, K.

AU - Makino, H.

AU - Kumagai, I.

AU - Haramoto, T.

AU - Yamasaki, Y.

AU - Shikata, K.

AU - Takahashi, M.

AU - Nishii, M.

AU - Ota, Z.

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AB - A 29‐year‐old diabetic woman who developed severe anaemia, nephrotic syndrome, and hypertension before the 28th week of gestation, had residual evidence of toxaemia and renal dysfunction more than 1 month following delivery. The histopathological findings of renal biopsy specimens were considered most consistent with toxaemia of pregnancy complicated by diabetic glomerulosclerosis. We consider that rapid acceleration of renal dysfunction may have been induced by: (1) poor control of diabetes before pregnancy; (2) glomerular hyperfiltration of the remnant nephrons throughout pregnancy; (3) hypercoagulopathy associated with pregnancy; (4) appearance of hypertension following these three conditions. 1992 Diabetes UK

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KW - Toxaemia of pregnancy

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A Case of Nephrotic Syndrome and Renal Dysfunction in a Pregnant Woman with Diabetes Mellitus

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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