A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery

Kensuke Uraguchi; Kenichi Kozakura; Satoshi Oka; Takaya Higaki; Seiichiro Makihara; Toshi Imai; Akira Doi; Tsuyoshi Ohta; Shin Kariya; Kazunori Nishizaki

doi:10.1016/j.mmcr.2020.09.004

A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery

Kensuke Uraguchi, Kenichi Kozakura, Satoshi Oka, Takaya Higaki, Seiichiro Makihara, Toshi Imai, Akira Doi, Tsuyoshi Ohta, Shin Kariya, Kazunori Nishizaki

Research output: Contribution to journal › Article › peer-review

Abstract

A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. Successful endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findings showed the mucormycosis.

Original language	English
Pages (from-to)	22-25
Number of pages	4
Journal	Medical Mycology Case Reports
Volume	30
DOIs	https://doi.org/10.1016/j.mmcr.2020.09.004
Publication status	Published - Dec 2020

Keywords

Acute monocytic leukemia
Acute rhinosinusitis
Brain abscess
Endoscopic endonasal skull base surgery
Rhinocerebral mucormycosis

ASJC Scopus subject areas

Microbiology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.mmcr.2020.09.004

Cite this

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title = "A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery",

abstract = "A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. Successful endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findings showed the mucormycosis.",

keywords = "Acute monocytic leukemia, Acute rhinosinusitis, Brain abscess, Endoscopic endonasal skull base surgery, Rhinocerebral mucormycosis",

author = "Kensuke Uraguchi and Kenichi Kozakura and Satoshi Oka and Takaya Higaki and Seiichiro Makihara and Toshi Imai and Akira Doi and Tsuyoshi Ohta and Shin Kariya and Kazunori Nishizaki",

note = "Funding Information: This work was supported by JSPS KAKENHI (Grants in aid for scientific research). Grant Number JP17K11329 . Publisher Copyright: {\textcopyright} 2020 The Authors",

year = "2020",

month = dec,

doi = "10.1016/j.mmcr.2020.09.004",

language = "English",

volume = "30",

pages = "22--25",

journal = "Medical Mycology Case Reports",

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T1 - A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery

AU - Uraguchi, Kensuke

AU - Kozakura, Kenichi

AU - Oka, Satoshi

AU - Higaki, Takaya

AU - Makihara, Seiichiro

AU - Imai, Toshi

AU - Doi, Akira

AU - Ohta, Tsuyoshi

AU - Kariya, Shin

AU - Nishizaki, Kazunori

PY - 2020/12

Y1 - 2020/12

N2 - A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. Successful endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findings showed the mucormycosis.

AB - A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. Successful endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findings showed the mucormycosis.

KW - Acute monocytic leukemia

KW - Acute rhinosinusitis

KW - Brain abscess

KW - Endoscopic endonasal skull base surgery

KW - Rhinocerebral mucormycosis

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JO - Medical Mycology Case Reports

JF - Medical Mycology Case Reports

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A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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