A Case of Systemic Sclerosis Complicated with Antiphospholipid Antibody Syndrome

Ryo Tanaka, Takenobu Yamamoto, Osamu Yamasaki, Joji Tada, Jiro Arata, Yasuhiro Manabe

Research output: Contribution to journalArticlepeer-review


We report a case of systemic sclerosis complicated with antiphospholipid syndrome in a 50-year-old woman. She showed multiple signs and symptoms stich as sclerodactylia, a mask-like face, poikiloderma, multiple skin ulcers, interstitial pneumonia, sick sinus syndrome, and esophageal dysfunction. Both antinuclear antibody and lupus anticoagulant were positive. Initially we diagnosed her with systemic sclerosis. We treated the patient with prednisolone at a dose of 20-40 mg/day, and added steroid pulse therapy three times. Unfortunately, the patient died of pulmonary thromboembolism. We finally diagnosed her to have antiphospholipid antibody syndrome.

Original languageEnglish
Pages (from-to)230-234
Number of pages5
JournalNishinihon Journal of Dermatology
Issue number3
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Dermatology


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