A combined light and scanning electron microscopy on human urinary cytology

Hiromi Kumon1, Yasutomo Nasu, Yosuke Matsumura, Hiroyuki Ohmori, Toshio Tanaka

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Approximately 250 bladder-washing and voided urine specimens from normal, and inflammatory and malignant lesions were examined using light microscopy (LM), scanning electron microscopy (SEM) and a newly-designed mesh. This specific mesh, containing 42 compartments in 25 mm2 on gelatine- coated glass-slip, permitted us the direct correlation of LM and SEM images. With SEM, malignancy of exfoliated urothelial cells mainly depended on the presence or absence of pleomorphic microvilli. Subsequently, a new “SEM grading” regarding human urinary cytology was proposed.

Original languageEnglish
Pages (from-to)27-32
Number of pages6
Issue number1
Publication statusPublished - 1983


  • Human bladder cancer
  • Pleomorphic microvilli
  • Scanning electron microscopy (SEM)
  • Urinary cytology

ASJC Scopus subject areas

  • Structural Biology
  • Instrumentation
  • Radiology Nuclear Medicine and imaging


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