A concise approach to (±)-tubifoline based on the palladium-catalyzed cross-coupling reaction of indolylborate

Minoru Ishikura; Norinobu Takahashi; Koji Yamada; Takumi Abe

doi:10.3987/COM-07-11190

A concise approach to (±)-tubifoline based on the palladium-catalyzed cross-coupling reaction of indolylborate

Minoru Ishikura, Norinobu Takahashi, Koji Yamada, Takumi Abe

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

The palladium-catalyzed tandem cyclization-cross-coupling protocol using 1H-indol-2-yltrialkylborate (indolylborate) proved to be a versatile approach to the generation of 2-(4-piperidylmethyl)indole, which was successfully used for the preparation of (±)-tubifoline.

Original language	English
Pages (from-to)	107-118
Number of pages	12
Journal	Heterocycles
Volume	75
Issue number	1
DOIs	https://doi.org/10.3987/COM-07-11190
Publication status	Published - Jan 1 2008
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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10.3987/COM-07-11190

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abstract = "The palladium-catalyzed tandem cyclization-cross-coupling protocol using 1H-indol-2-yltrialkylborate (indolylborate) proved to be a versatile approach to the generation of 2-(4-piperidylmethyl)indole, which was successfully used for the preparation of (±)-tubifoline.",

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AU - Yamada, Koji

AU - Abe, Takumi

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A concise approach to (±)-tubifoline based on the palladium-catalyzed cross-coupling reaction of indolylborate

Abstract

ASJC Scopus subject areas

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