A cost-minimization analysis of measures against metallic dental restorations for head and neck radiotherapy

Kouji Katsura, Yoshihiko Soga, Sadatomo Zenda, Hiromi Nishi, Marie Soga, Masatoshi Usubuchi, Sachiyo Mitsunaga, Ken Tomizuka, Tetsuhito Konishi, Wakako Yatsuoka, Takao Ueno, Tadanobu Aragaki, Takafumi Hayashi

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The aim of this study was to compare the estimated public medical care cost of measures to address metallic dental restorations (MDRs) for head and neck radiotherapy using high-energy mega-voltage X-rays. This was considered a first step to clarify which MDR measure was more cost-effective. We estimated the medical care cost of radiotherapy for two representative MDR measures: (i) with MDR removal or (ii) without MDR removal (non-MDR removal) using magnetic resonance imaging and a spacer. A total of 5520 patients received head and neck radiation therapy in 2018. The mean number of MDRs per person was 4.1 dental crowns and 1.3 dental bridges. The mean cost per person was estimated to be 121 720 yen for MDR removal and 54 940 yen for non-MDR removal. Therefore, the difference in total public medical care cost between MDR removal and non-MDR removal was estimated to be 303 268 800 yen. Our results suggested that non-MDR removal would be more cost-effective than MDR removal for head and neck radiotherapy. In the future, a national survey and cost-effectiveness analysis via a multicenter study are necessary; these investigations should include various outcomes such as the rate of local control, status of oral mucositis, frequency of hospital visits and efforts of the medical professionals.

Original languageEnglish
Pages (from-to)374-378
Number of pages5
JournalJournal of radiation research
Issue number2
Publication statusPublished - Mar 10 2021


  • head and neck radiotherapy
  • magnetic resonance imaging
  • metallic dental restoration
  • mouthpiece
  • public medical care cost

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Health, Toxicology and Mutagenesis


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