TY - JOUR
T1 - A Hepatoportal osmoreceptive afferent projection from nucleus tractus solitarius to caudal ventrolateral medulla
AU - Kobashi, Motoi
AU - Adachi, Akira
PY - 1990/6
Y1 - 1990/6
N2 - This study was performed to examine projection of nucleus tractus solitarii (NTS) neurons to the caudal ventrolateral medulla (cVLM) in rats. One hundred and seven neurons that responded antidromically to electrical stimulation of the cVLM were recorded within the NTS. Electrical stimulation of the hepatic branch of the vagus nerve (hepatic vagus) elicited facilitation on 62 neurons (facilitatory neurons) and suppression on 6 neurons (suppressed neurons). Effect of portal infusion of hypertonic saline was examined on 44 facilitatory and 4 suppressed neurons. Twelve facilitatory and 2 suppressed neurons showed a decrease in the discharge rate. One suppressed neuron showed an increase in the discharge rate. It is concluded that hepatoportal osmoreceptive signals are conveyed from the NTS to the cVLM. The responses are mostly characterized by the decrease in the discharge rate by portal infusion of hypertonic saline.
AB - This study was performed to examine projection of nucleus tractus solitarii (NTS) neurons to the caudal ventrolateral medulla (cVLM) in rats. One hundred and seven neurons that responded antidromically to electrical stimulation of the cVLM were recorded within the NTS. Electrical stimulation of the hepatic branch of the vagus nerve (hepatic vagus) elicited facilitation on 62 neurons (facilitatory neurons) and suppression on 6 neurons (suppressed neurons). Effect of portal infusion of hypertonic saline was examined on 44 facilitatory and 4 suppressed neurons. Twelve facilitatory and 2 suppressed neurons showed a decrease in the discharge rate. One suppressed neuron showed an increase in the discharge rate. It is concluded that hepatoportal osmoreceptive signals are conveyed from the NTS to the cVLM. The responses are mostly characterized by the decrease in the discharge rate by portal infusion of hypertonic saline.
KW - Hepatic vagus
KW - Hepatoportal osmoreceptor
KW - Nucleus tractus solitarius
KW - Ventrolateral medulla
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U2 - 10.1016/0361-9230(90)90139-Q
DO - 10.1016/0361-9230(90)90139-Q
M3 - Article
C2 - 2372696
AN - SCOPUS:0025368410
SN - 0361-9230
VL - 24
SP - 775
EP - 778
JO - Journal of Electrophysiological Techniques
JF - Journal of Electrophysiological Techniques
IS - 6
ER -