TY - JOUR
T1 - A Long-Term Survival Case of Coronary Artery Intimal Sarcoma
AU - Nakashima, Mitsutaka
AU - Nakamura, Kazufumi
AU - Tabata, Masahiro
AU - Masuda, Zen-ichi
AU - Tanaka, Takehiro
AU - Yoshida, Masatoki
AU - Maeda, Yoshinobu
AU - Kasahara, Shingo
AU - Itoh, Hiroshi
N1 - Publisher Copyright:
© 2023, International Heart Journal Association. All rights reserved.
PY - 2023
Y1 - 2023
N2 - Summary Primary cardiac sarcomas are rare diseases with very poor prognoses. In this report, we present a case of coronary artery intimal sarcoma in a patient who survived for a long time after diagnosis. A 57-year-old female underwent percutaneous coronary intervention of the right coronary artery due to acute myocardial infarction caused by thrombotic occlusion and was diagnosed as having coronary artery intimal sarcoma. She underwent surgical resection and coronary artery bypass surgery of the artery, cryothermy coagulation, and postoperative adjuvant chemotherapy for 1 year. After 3 years, focal recurrence was detected in the caudal region of the left ventricular inferior wall. Radiotherapy was performed. The tumor shrank significantly after radiotherapy. Four years later, there was no significant abnormal uptake on positron-emission tomography/computed tomography. At 7 years after diagnosis, when this case report was submitted, the patient was alive and her performance had maintained a good status. Intimal sarcoma occurring in a coronary artery is extremely rare. The efficacy of treatments for cardiac intimal sarcoma, which include surgical resection, chemotherapy and radiotherapy, has been reported to be limited. To the best of our knowledge, this is the first report of a case of coronary artery in-timal sarcoma with long-term survival after comprehensive therapies including surgical resection and radiother-apy.
AB - Summary Primary cardiac sarcomas are rare diseases with very poor prognoses. In this report, we present a case of coronary artery intimal sarcoma in a patient who survived for a long time after diagnosis. A 57-year-old female underwent percutaneous coronary intervention of the right coronary artery due to acute myocardial infarction caused by thrombotic occlusion and was diagnosed as having coronary artery intimal sarcoma. She underwent surgical resection and coronary artery bypass surgery of the artery, cryothermy coagulation, and postoperative adjuvant chemotherapy for 1 year. After 3 years, focal recurrence was detected in the caudal region of the left ventricular inferior wall. Radiotherapy was performed. The tumor shrank significantly after radiotherapy. Four years later, there was no significant abnormal uptake on positron-emission tomography/computed tomography. At 7 years after diagnosis, when this case report was submitted, the patient was alive and her performance had maintained a good status. Intimal sarcoma occurring in a coronary artery is extremely rare. The efficacy of treatments for cardiac intimal sarcoma, which include surgical resection, chemotherapy and radiotherapy, has been reported to be limited. To the best of our knowledge, this is the first report of a case of coronary artery in-timal sarcoma with long-term survival after comprehensive therapies including surgical resection and radiother-apy.
KW - Chemotherapy
KW - Cryothermy coagulation
KW - Radiotherapy
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U2 - 10.1536/ihj.22-578
DO - 10.1536/ihj.22-578
M3 - Article
C2 - 37197917
AN - SCOPUS:85160964941
SN - 1349-2365
VL - 64
SP - 483
EP - 486
JO - International heart journal
JF - International heart journal
IS - 3
ER -