A multicenter prospective cohort study on the effect of smoking cessation on periodontal therapies in japan

Yohei Nakayama, Koji Mizutani, Yuka Tsumanuma, Hiroyuki Yoshino, Norio Aoyama, Koji Inagaki, Manabu Morita, Yuichi Izumi, Shinya Murakami, Hidenori Yoshimura, Takanori Matsuura, Takashi Murakami, Matsuo Yamamoto, Nobuo Yoshinari, Masaru Mezawa, Yorimasa Ogata, Atsutoshi Yoshimura, Kanji Kono, Kosuke Maruyama, Soh SatoRyuji Sakagami, Hiroshi Ito, Yukihiro Numabe, Masahiko Nikaido, Takashi Hanioka, Kanichi Seto, Jinichi Fukuda, Saman Warnakulasuriya, Toru Nagao

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Few prospective studies have reported the effects of periodontal therapy on patients who attempted to quit smoking. This study aimed to assess how smoking cessation affects periodontal therapy. Twenty-five smokers with periodontitis were investigated by dividing them into two groups, a smoking cessation support group and a continued smoking group. Those in the support group received counseling and nicotine replacement therapy, followed by periodontal treatment conducted by dentists who had completed an e-learning course on smoking cessation. Clinical parameters were measured at baseline, 3, and 6 months. Most clinical parameters improved for those in the smoking cessation support group. There were no significant improvements in bleeding on probing (BOP) or the number of severe periodontal disease sites in the continued smoking group. Probing pocket depth (PPD) and clinical attachment levels (CAL) at sites that received scaling and root planing (SRP) significantly improved in all subjects. BOP did not improve at reevaluation in the smoking relapse subgroup. Patients in the smoking cessation support program led by dental professionals showed more improvement in BOP than those in the continued smoking group.

Original languageEnglish
Pages (from-to)114-118
Number of pages5
JournalJournal of Oral Science
Issue number1
Publication statusPublished - 2021


  • ; dental setting
  • Multicenter study
  • Periodontal therapy
  • Smoking cessation
  • Support

ASJC Scopus subject areas

  • Dentistry(all)


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