A new route to 3-acyl-2-aminobenzofurans: Palladium-catalysed cycloisomerisation of 2-(cyanomethyl)phenyl esters

Masahito Murai; Koji Miki; Kouichi Ohe

doi:10.1039/b904127c

A new route to 3-acyl-2-aminobenzofurans: Palladium-catalysed cycloisomerisation of 2-(cyanomethyl)phenyl esters

Masahito Murai, Koji Miki, Kouichi Ohe

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

Treatment of 2-(cyanomethyl)phenyl esters with a catalytic amount of Pd(OAc)₂, PCy₃, and Zn afforded 3-acyl-2-aminobenzofuran derivatives in good to excellent yields, which can be used as building blocks for the synthesis of benzofuran fused heterocycles.

Original language	English
Pages (from-to)	3466-3468
Number of pages	3
Journal	Chemical Communications
Issue number	23
DOIs	https://doi.org/10.1039/b904127c
Publication status	Published - Aug 7 2009

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b904127c

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title = "A new route to 3-acyl-2-aminobenzofurans: Palladium-catalysed cycloisomerisation of 2-(cyanomethyl)phenyl esters",

abstract = "Treatment of 2-(cyanomethyl)phenyl esters with a catalytic amount of Pd(OAc)2, PCy3, and Zn afforded 3-acyl-2-aminobenzofuran derivatives in good to excellent yields, which can be used as building blocks for the synthesis of benzofuran fused heterocycles.",

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AB - Treatment of 2-(cyanomethyl)phenyl esters with a catalytic amount of Pd(OAc)2, PCy3, and Zn afforded 3-acyl-2-aminobenzofuran derivatives in good to excellent yields, which can be used as building blocks for the synthesis of benzofuran fused heterocycles.

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A new route to 3-acyl-2-aminobenzofurans: Palladium-catalysed cycloisomerisation of 2-(cyanomethyl)phenyl esters

Abstract

ASJC Scopus subject areas

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