A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata

Zhi Yu Ni; Mei Dong; Bin Cong; Franoise Sauriol; Man Li Zhang; Yu Fang Wang; Chang Hong Huo; Qing Wen Shi; Hiromasa Kiyota

doi:10.1055/s-0030-1250333

A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata

Zhi Yu Ni, Mei Dong, Bin Cong, Franoise Sauriol, Man Li Zhang, Yu Fang Wang, Chang Hong Huo, Qing Wen Shi, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Three new taxanes, 2α,9α,10β-triacetoxy-13α-(β- D-glucopyranosyloxy)taxa-4(20),11-dien-5α-ol (1), 5α,10β, 13α-triacetoxytax-11-ene-2α,7β,9α,20-tetraol (2), and 5α,10β,13β-triacetoxy-2α,7β-dihydroxy-2(3→20) abeotaxa-4(20),11-dien-9-one (3), were isolated from the leaves of the Japanese yew, Taxus cuspidata. Compound 1 is the first example of a taxane with 13-glycosidic linkage.

Original language	English
Pages (from-to)	281-283
Number of pages	3
Journal	Planta Medica
Volume	77
Issue number	3
DOIs	https://doi.org/10.1055/s-0030-1250333
Publication status	Published - Jan 1 2011
Externally published	Yes

Keywords

Taxaceae
Taxus cuspidata
leaves
taxane glucoside
taxanes
yew

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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title = "A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata",

abstract = "Three new taxanes, 2α,9α,10β-triacetoxy-13α-(β- D-glucopyranosyloxy)taxa-4(20),11-dien-5α-ol (1), 5α,10β, 13α-triacetoxytax-11-ene-2α,7β,9α,20-tetraol (2), and 5α,10β,13β-triacetoxy-2α,7β-dihydroxy-2(3→20) abeotaxa-4(20),11-dien-9-one (3), were isolated from the leaves of the Japanese yew, Taxus cuspidata. Compound 1 is the first example of a taxane with 13-glycosidic linkage.",

keywords = "Taxaceae, Taxus cuspidata, leaves, taxane glucoside, taxanes, yew",

author = "Ni, {Zhi Yu} and Mei Dong and Bin Cong and Franoise Sauriol and Zhang, {Man Li} and Wang, {Yu Fang} and Huo, {Chang Hong} and Shi, {Qing Wen} and Hiromasa Kiyota",

year = "2011",

month = jan,

day = "1",

doi = "10.1055/s-0030-1250333",

language = "English",

volume = "77",

pages = "281--283",

journal = "Planta Medica",

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publisher = "Georg Thieme Verlag",

number = "3",

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TY - JOUR

T1 - A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata

AU - Ni, Zhi Yu

AU - Dong, Mei

AU - Cong, Bin

AU - Sauriol, Franoise

AU - Zhang, Man Li

AU - Wang, Yu Fang

AU - Huo, Chang Hong

AU - Shi, Qing Wen

AU - Kiyota, Hiromasa

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Three new taxanes, 2α,9α,10β-triacetoxy-13α-(β- D-glucopyranosyloxy)taxa-4(20),11-dien-5α-ol (1), 5α,10β, 13α-triacetoxytax-11-ene-2α,7β,9α,20-tetraol (2), and 5α,10β,13β-triacetoxy-2α,7β-dihydroxy-2(3→20) abeotaxa-4(20),11-dien-9-one (3), were isolated from the leaves of the Japanese yew, Taxus cuspidata. Compound 1 is the first example of a taxane with 13-glycosidic linkage.

AB - Three new taxanes, 2α,9α,10β-triacetoxy-13α-(β- D-glucopyranosyloxy)taxa-4(20),11-dien-5α-ol (1), 5α,10β, 13α-triacetoxytax-11-ene-2α,7β,9α,20-tetraol (2), and 5α,10β,13β-triacetoxy-2α,7β-dihydroxy-2(3→20) abeotaxa-4(20),11-dien-9-one (3), were isolated from the leaves of the Japanese yew, Taxus cuspidata. Compound 1 is the first example of a taxane with 13-glycosidic linkage.

KW - Taxaceae

KW - Taxus cuspidata

KW - leaves

KW - taxane glucoside

KW - taxanes

KW - yew

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U2 - 10.1055/s-0030-1250333

DO - 10.1055/s-0030-1250333

M3 - Article

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AN - SCOPUS:79951512715

SN - 0032-0943

VL - 77

SP - 281

EP - 283

JO - Planta Medica

JF - Planta Medica

IS - 3

ER -

A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata

Abstract

Keywords

ASJC Scopus subject areas

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