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A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata

  • Zhi Yu Ni
  • , Mei Dong
  • , Bin Cong
  • , Franoise Sauriol
  • , Man Li Zhang
  • , Yu Fang Wang
  • , Chang Hong Huo
  • , Qing Wen Shi
  • , Hiromasa Kiyota

Research output: Contribution to journalArticlepeer-review

Abstract

Three new taxanes, 2α,9α,10β-triacetoxy-13α-(β- D-glucopyranosyloxy)taxa-4(20),11-dien-5α-ol (1), 5α,10β, 13α-triacetoxytax-11-ene-2α,7β,9α,20-tetraol (2), and 5α,10β,13β-triacetoxy-2α,7β-dihydroxy-2(3→20) abeotaxa-4(20),11-dien-9-one (3), were isolated from the leaves of the Japanese yew, Taxus cuspidata. Compound 1 is the first example of a taxane with 13-glycosidic linkage.

Original languageEnglish
Pages (from-to)281-283
Number of pages3
JournalPlanta Medica
Volume77
Issue number3
DOIs
Publication statusPublished - 2011
Externally publishedYes

Keywords

  • Taxaceae
  • Taxus cuspidata
  • leaves
  • taxane glucoside
  • taxanes
  • yew

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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