A spontaneous recovery of anti-galactocerebroside antibody-associated encephalitis without evidence of Mycoplasma infection

Koh Tadokoro; Yoshio Omote; Yosuke Osakada; Ken Ikegami; Kota Sato; Mami Takemoto; Nozomi Hishikawa; Yasuyuki Ohta; Toru Yamashita; Koji Abe

doi:10.1111/ncn3.12379

A spontaneous recovery of anti-galactocerebroside antibody-associated encephalitis without evidence of Mycoplasma infection

Koh Tadokoro
, Yoshio Omote
, Yosuke Osakada
, Ken Ikegami
, Kota Sato
, Mami Takemoto
, Nozomi Hishikawa
, Yasuyuki Ohta
, Toru Yamashita
, Koji Abe

Research output: Contribution to journal › Article › peer-review

Abstract

Anti-galactocerebroside (Gal-C) antibody is characteristic of encephalomyelitis and Guillain-Barré syndrome subsequent to mycoplasma infection. Here, we report a 75-year-old Japanese man who presented somnolence, signs of meningeal irritation, and parkinsonian features with positive serum inflammatory markers and cerebrospinal fluid (CSF) pleocytosis. Although anti-Mycoplasma pneumoniae antibody was negative, anti-Gal-C antibody was later detected in his serum. The present case recovered spontaneously without any other specific therapies.

Original language	English
Pages (from-to)	164-166
Number of pages	3
Journal	Neurology and Clinical Neuroscience
Volume	8
Issue number	3
DOIs	https://doi.org/10.1111/ncn3.12379
Publication status	Published - May 1 2020

Keywords

antibodies
encephalitis
galactocerebroside
infection
mycoplasma

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1111/ncn3.12379

Cite this

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title = "A spontaneous recovery of anti-galactocerebroside antibody-associated encephalitis without evidence of Mycoplasma infection",

abstract = "Anti-galactocerebroside (Gal-C) antibody is characteristic of encephalomyelitis and Guillain-Barr{\'e} syndrome subsequent to mycoplasma infection. Here, we report a 75-year-old Japanese man who presented somnolence, signs of meningeal irritation, and parkinsonian features with positive serum inflammatory markers and cerebrospinal fluid (CSF) pleocytosis. Although anti-Mycoplasma pneumoniae antibody was negative, anti-Gal-C antibody was later detected in his serum. The present case recovered spontaneously without any other specific therapies.",

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AU - Tadokoro, Koh

AU - Omote, Yoshio

AU - Osakada, Yosuke

AU - Ikegami, Ken

AU - Sato, Kota

AU - Takemoto, Mami

AU - Hishikawa, Nozomi

AU - Ohta, Yasuyuki

AU - Yamashita, Toru

AU - Abe, Koji

PY - 2020/5/1

Y1 - 2020/5/1

N2 - Anti-galactocerebroside (Gal-C) antibody is characteristic of encephalomyelitis and Guillain-Barré syndrome subsequent to mycoplasma infection. Here, we report a 75-year-old Japanese man who presented somnolence, signs of meningeal irritation, and parkinsonian features with positive serum inflammatory markers and cerebrospinal fluid (CSF) pleocytosis. Although anti-Mycoplasma pneumoniae antibody was negative, anti-Gal-C antibody was later detected in his serum. The present case recovered spontaneously without any other specific therapies.

AB - Anti-galactocerebroside (Gal-C) antibody is characteristic of encephalomyelitis and Guillain-Barré syndrome subsequent to mycoplasma infection. Here, we report a 75-year-old Japanese man who presented somnolence, signs of meningeal irritation, and parkinsonian features with positive serum inflammatory markers and cerebrospinal fluid (CSF) pleocytosis. Although anti-Mycoplasma pneumoniae antibody was negative, anti-Gal-C antibody was later detected in his serum. The present case recovered spontaneously without any other specific therapies.

KW - antibodies

KW - encephalitis

KW - galactocerebroside

KW - infection

KW - mycoplasma

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A spontaneous recovery of anti-galactocerebroside antibody-associated encephalitis without evidence of Mycoplasma infection

Abstract

Keywords

ASJC Scopus subject areas

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