A Versatile Terahertz Chemical Microscope and Its Application for the Detection of Histamine

Jin Wang; Kosuke Sato; Yuichi Yoshida; Kenji Sakai; Toshihiko Kiwa

doi:10.3390/photonics9010026

A Versatile Terahertz Chemical Microscope and Its Application for the Detection of Histamine

Jin Wang, Kosuke Sato, Yuichi Yoshida, Kenji Sakai, Toshihiko Kiwa

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Terahertz waves have gained increasingly more attention because of their unique characteristics and great potential in a variety of fields. In this study, we introduced the recent progress of our versatile terahertz chemical microscope (TCM) in the detection of small biomolecules, ions, cancer cells, and antibody–antigen immunoassaying. We highlight the advantages of our TCM for chemical sensing and biosensing, such as label-free, high-sensitivity, rapid response, non-pretreatment, and minute amount sample consumption, compared with conventional methods. Furthermore, we demonstrated its new application in detection of allergic-related histamine at low concentration in buffer solutions.

Original language	English
Article number	26
Journal	Photonics
Volume	9
Issue number	1
DOIs	https://doi.org/10.3390/photonics9010026
Publication status	Published - Jan 2022

Keywords

Antibody–antigen
Biological substances
Cancer cells
Histamine
Label-free
Potential distribution
Terahertz chemical microscope

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Instrumentation
Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/photonics9010026

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title = "A Versatile Terahertz Chemical Microscope and Its Application for the Detection of Histamine",

abstract = "Terahertz waves have gained increasingly more attention because of their unique characteristics and great potential in a variety of fields. In this study, we introduced the recent progress of our versatile terahertz chemical microscope (TCM) in the detection of small biomolecules, ions, cancer cells, and antibody–antigen immunoassaying. We highlight the advantages of our TCM for chemical sensing and biosensing, such as label-free, high-sensitivity, rapid response, non-pretreatment, and minute amount sample consumption, compared with conventional methods. Furthermore, we demonstrated its new application in detection of allergic-related histamine at low concentration in buffer solutions.",

keywords = "Antibody–antigen, Biological substances, Cancer cells, Histamine, Label-free, Potential distribution, Terahertz chemical microscope",

author = "Jin Wang and Kosuke Sato and Yuichi Yoshida and Kenji Sakai and Toshihiko Kiwa",

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T1 - A Versatile Terahertz Chemical Microscope and Its Application for the Detection of Histamine

AU - Wang, Jin

AU - Sato, Kosuke

AU - Yoshida, Yuichi

AU - Sakai, Kenji

AU - Kiwa, Toshihiko

PY - 2022/1

Y1 - 2022/1

N2 - Terahertz waves have gained increasingly more attention because of their unique characteristics and great potential in a variety of fields. In this study, we introduced the recent progress of our versatile terahertz chemical microscope (TCM) in the detection of small biomolecules, ions, cancer cells, and antibody–antigen immunoassaying. We highlight the advantages of our TCM for chemical sensing and biosensing, such as label-free, high-sensitivity, rapid response, non-pretreatment, and minute amount sample consumption, compared with conventional methods. Furthermore, we demonstrated its new application in detection of allergic-related histamine at low concentration in buffer solutions.

AB - Terahertz waves have gained increasingly more attention because of their unique characteristics and great potential in a variety of fields. In this study, we introduced the recent progress of our versatile terahertz chemical microscope (TCM) in the detection of small biomolecules, ions, cancer cells, and antibody–antigen immunoassaying. We highlight the advantages of our TCM for chemical sensing and biosensing, such as label-free, high-sensitivity, rapid response, non-pretreatment, and minute amount sample consumption, compared with conventional methods. Furthermore, we demonstrated its new application in detection of allergic-related histamine at low concentration in buffer solutions.

KW - Antibody–antigen

KW - Biological substances

KW - Cancer cells

KW - Histamine

KW - Label-free

KW - Potential distribution

KW - Terahertz chemical microscope

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A Versatile Terahertz Chemical Microscope and Its Application for the Detection of Histamine

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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