Ablation of Kidney Tumors in Patients with Substantial Kidney Impairment: Current Status

Toshihiro Iguchi; Yusuke Matsui; Koji Tomita; Mayu Uka; Noriyuki Umakoshi; Takahiro Kawabata; Hideo Gobara; Motoo Araki; Takao Hiraki

doi:10.1007/s11912-024-01533-6

Ablation of Kidney Tumors in Patients with Substantial Kidney Impairment: Current Status

Toshihiro Iguchi, Yusuke Matsui, Koji Tomita, Mayu Uka, Noriyuki Umakoshi, Takahiro Kawabata, Hideo Gobara, Motoo Araki, Takao Hiraki

Research output: Contribution to journal › Review article › peer-review

Abstract

Purpose of review: To review the current status of kidney tumor ablation in patients with substantial kidney impairment. Recent findings: Few reports of kidney tumor ablation in such patients have recently been published. The reported prevalence of patients with stage 4 or 5 chronic kidney disease (CKD) among patients undergoing ablation is 2.0%–10%. In patients with stage 4 or 5 CKD, local tumor control rates were 88%–100%. The effect of ablation on CKD stage is unclear, and the observed deteriorations in kidney function are consistent with both the effect of cryoablation and the natural course of advanced CKD. Summary: According to guidelines, active surveillance may be selected. The goals of treatment are complete tumor removal and maintenance of kidney function, both of which can be met by ablation. Given the limited treatment options, ablation may play a pivotal role in the management of patients with advanced CKD.

Original language	English
Pages (from-to)	573-582
Number of pages	10
Journal	Current Oncology Reports
Volume	26
Issue number	5
DOIs	https://doi.org/10.1007/s11912-024-01533-6
Publication status	Published - May 2024

Keywords

Ablation
Kidney
Renal cell carcinoma
Renal impairment
Tumor

ASJC Scopus subject areas

Oncology

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10.1007/s11912-024-01533-6

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title = "Ablation of Kidney Tumors in Patients with Substantial Kidney Impairment: Current Status",

abstract = "Purpose of review: To review the current status of kidney tumor ablation in patients with substantial kidney impairment. Recent findings: Few reports of kidney tumor ablation in such patients have recently been published. The reported prevalence of patients with stage 4 or 5 chronic kidney disease (CKD) among patients undergoing ablation is 2.0%–10%. In patients with stage 4 or 5 CKD, local tumor control rates were 88%–100%. The effect of ablation on CKD stage is unclear, and the observed deteriorations in kidney function are consistent with both the effect of cryoablation and the natural course of advanced CKD. Summary: According to guidelines, active surveillance may be selected. The goals of treatment are complete tumor removal and maintenance of kidney function, both of which can be met by ablation. Given the limited treatment options, ablation may play a pivotal role in the management of patients with advanced CKD.",

keywords = "Ablation, Kidney, Renal cell carcinoma, Renal impairment, Tumor",

author = "Toshihiro Iguchi and Yusuke Matsui and Koji Tomita and Mayu Uka and Noriyuki Umakoshi and Takahiro Kawabata and Hideo Gobara and Motoo Araki and Takao Hiraki",

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AU - Iguchi, Toshihiro

AU - Matsui, Yusuke

AU - Tomita, Koji

AU - Uka, Mayu

AU - Umakoshi, Noriyuki

AU - Kawabata, Takahiro

AU - Gobara, Hideo

AU - Araki, Motoo

AU - Hiraki, Takao

N1 - Publisher Copyright: © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.

PY - 2024/5

Y1 - 2024/5

N2 - Purpose of review: To review the current status of kidney tumor ablation in patients with substantial kidney impairment. Recent findings: Few reports of kidney tumor ablation in such patients have recently been published. The reported prevalence of patients with stage 4 or 5 chronic kidney disease (CKD) among patients undergoing ablation is 2.0%–10%. In patients with stage 4 or 5 CKD, local tumor control rates were 88%–100%. The effect of ablation on CKD stage is unclear, and the observed deteriorations in kidney function are consistent with both the effect of cryoablation and the natural course of advanced CKD. Summary: According to guidelines, active surveillance may be selected. The goals of treatment are complete tumor removal and maintenance of kidney function, both of which can be met by ablation. Given the limited treatment options, ablation may play a pivotal role in the management of patients with advanced CKD.

AB - Purpose of review: To review the current status of kidney tumor ablation in patients with substantial kidney impairment. Recent findings: Few reports of kidney tumor ablation in such patients have recently been published. The reported prevalence of patients with stage 4 or 5 chronic kidney disease (CKD) among patients undergoing ablation is 2.0%–10%. In patients with stage 4 or 5 CKD, local tumor control rates were 88%–100%. The effect of ablation on CKD stage is unclear, and the observed deteriorations in kidney function are consistent with both the effect of cryoablation and the natural course of advanced CKD. Summary: According to guidelines, active surveillance may be selected. The goals of treatment are complete tumor removal and maintenance of kidney function, both of which can be met by ablation. Given the limited treatment options, ablation may play a pivotal role in the management of patients with advanced CKD.

KW - Ablation

KW - Kidney

KW - Renal cell carcinoma

KW - Renal impairment

KW - Tumor

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Ablation of Kidney Tumors in Patients with Substantial Kidney Impairment: Current Status

Abstract

Keywords

ASJC Scopus subject areas

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