TY - JOUR
T1 - Acute flaccid myelitis associated with enterovirus D68 in a non-epidemic setting
AU - Hatayama, Kazuki
AU - Goto, Shinichiro
AU - Yashiro, Masato
AU - Mori, Harushi
AU - Fujimoto, Tsuguto
AU - Hanaoka, Nozomu
AU - Tanaka-Taya, Keiko
AU - Zuzan, Tomoka
AU - Inoue, Masaru
N1 - Funding Information:
We thank all those involved in this study including the Okayama Red Cross Hospital Laboratory and the Okayama City Health Center staff. This study was partly supported by the AMED research program on Emerging and Re-emerging Infectious Disease (grant No. 10104402 , JP18fk0108004j0303 ) and the Health and Labor Sciences Research Grant from the Ministry of Health, Labour and Welfare of Japan (grant number H28-Shinkogyosei-Ippan-007 ).
PY - 2019
Y1 - 2019
N2 - Acute flaccid myelitis (AFM)is a recently defined clinical disease accompanied by the national outbreak of enterovirus D68 (EV-D68)in the United States during the late summer/fall of 2014; 258 cases of EV-D68 and 59 cases of AFM were reported in Japan during the late summer/fall of 2015. Subsequently, there have been no epidemics of AFM or EV-D68. However, we encountered a patient who had AFM associated with EV-D68 in 2017. This is the first case of AFM caused by EV-D68 after the 2015 epidemic, and the only reported case in 2017. This report indicates that AFM caused by EV-D68 can arise even in non-epidemic situations. If a patient presents with paralysis, AFM caused by EV-D68 should be included in the differential diagnosis, regardless of the absence of an epidemic of EV-D68 infection.
AB - Acute flaccid myelitis (AFM)is a recently defined clinical disease accompanied by the national outbreak of enterovirus D68 (EV-D68)in the United States during the late summer/fall of 2014; 258 cases of EV-D68 and 59 cases of AFM were reported in Japan during the late summer/fall of 2015. Subsequently, there have been no epidemics of AFM or EV-D68. However, we encountered a patient who had AFM associated with EV-D68 in 2017. This is the first case of AFM caused by EV-D68 after the 2015 epidemic, and the only reported case in 2017. This report indicates that AFM caused by EV-D68 can arise even in non-epidemic situations. If a patient presents with paralysis, AFM caused by EV-D68 should be included in the differential diagnosis, regardless of the absence of an epidemic of EV-D68 infection.
KW - Acute flaccid myelitis
KW - Enterovirus D68
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U2 - 10.1016/j.idcr.2019.e00549
DO - 10.1016/j.idcr.2019.e00549
M3 - Article
AN - SCOPUS:85065247872
SN - 2214-2509
VL - 17
JO - IDCases
JF - IDCases
M1 - e00549
ER -
