Acute hepatitis due to hepatitis e virus genotype 1 as an imported infectious disease in Japan

Koji Miyahara; Yasuhiro Miyake; Tetsuya Yasunaka; Fusao Ikeda; Akinobu Takaki; Yoshiaki Iwasaki; Haruhiko Kobashi; Jong Hon Kang; Kazuaki Takahashi; Masahiro Arai; Kazuhide Yamamoto

doi:10.2169/internalmedicine.49.4221

Acute hepatitis due to hepatitis e virus genotype 1 as an imported infectious disease in Japan

Koji Miyahara, Yasuhiro Miyake, Tetsuya Yasunaka, Fusao Ikeda, Akinobu Takaki, Yoshiaki Iwasaki, Haruhiko Kobashi, Jong Hon Kang, Kazuaki Takahashi, Masahiro Arai, Kazuhide Yamamoto

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

An 18-year-old Nepalese man was admitted due to general malaise and anorexia a month after coming to Japan. Laboratory tests showed elevation of transaminase and positivity for IgM anti-HEV antibody. Serum HEV RNA was detected by RT-PCR amplifications. An HEV genome phylogenetic tree, constructed using an 821-nucleotide sequence in the open reading frame 1, indicated that the genotype was 1. HEV genotype 1 is epidemic in South Asia, Africa and South America, and the incidence of acute hepatitis due to HEV genotype 1 is low in Japan. Thereafter, attention should be paid to HEV genotype 1 infection as an imported infectious disease.

Original language	English
Pages (from-to)	2613-2616
Number of pages	4
Journal	Internal Medicine
Volume	49
Issue number	23
DOIs	https://doi.org/10.2169/internalmedicine.49.4221
Publication status	Published - 2010

Keywords

Acute hepatitis
Genotype
Hepatitis E virus

ASJC Scopus subject areas

Internal Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2169/internalmedicine.49.4221

Cite this

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title = "Acute hepatitis due to hepatitis e virus genotype 1 as an imported infectious disease in Japan",

abstract = "An 18-year-old Nepalese man was admitted due to general malaise and anorexia a month after coming to Japan. Laboratory tests showed elevation of transaminase and positivity for IgM anti-HEV antibody. Serum HEV RNA was detected by RT-PCR amplifications. An HEV genome phylogenetic tree, constructed using an 821-nucleotide sequence in the open reading frame 1, indicated that the genotype was 1. HEV genotype 1 is epidemic in South Asia, Africa and South America, and the incidence of acute hepatitis due to HEV genotype 1 is low in Japan. Thereafter, attention should be paid to HEV genotype 1 infection as an imported infectious disease.",

keywords = "Acute hepatitis, Genotype, Hepatitis E virus",

author = "Koji Miyahara and Yasuhiro Miyake and Tetsuya Yasunaka and Fusao Ikeda and Akinobu Takaki and Yoshiaki Iwasaki and Haruhiko Kobashi and Kang, {Jong Hon} and Kazuaki Takahashi and Masahiro Arai and Kazuhide Yamamoto",

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language = "English",

volume = "49",

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T1 - Acute hepatitis due to hepatitis e virus genotype 1 as an imported infectious disease in Japan

AU - Miyahara, Koji

AU - Miyake, Yasuhiro

AU - Yasunaka, Tetsuya

AU - Ikeda, Fusao

AU - Takaki, Akinobu

AU - Iwasaki, Yoshiaki

AU - Kobashi, Haruhiko

AU - Kang, Jong Hon

AU - Takahashi, Kazuaki

AU - Arai, Masahiro

AU - Yamamoto, Kazuhide

PY - 2010

Y1 - 2010

N2 - An 18-year-old Nepalese man was admitted due to general malaise and anorexia a month after coming to Japan. Laboratory tests showed elevation of transaminase and positivity for IgM anti-HEV antibody. Serum HEV RNA was detected by RT-PCR amplifications. An HEV genome phylogenetic tree, constructed using an 821-nucleotide sequence in the open reading frame 1, indicated that the genotype was 1. HEV genotype 1 is epidemic in South Asia, Africa and South America, and the incidence of acute hepatitis due to HEV genotype 1 is low in Japan. Thereafter, attention should be paid to HEV genotype 1 infection as an imported infectious disease.

AB - An 18-year-old Nepalese man was admitted due to general malaise and anorexia a month after coming to Japan. Laboratory tests showed elevation of transaminase and positivity for IgM anti-HEV antibody. Serum HEV RNA was detected by RT-PCR amplifications. An HEV genome phylogenetic tree, constructed using an 821-nucleotide sequence in the open reading frame 1, indicated that the genotype was 1. HEV genotype 1 is epidemic in South Asia, Africa and South America, and the incidence of acute hepatitis due to HEV genotype 1 is low in Japan. Thereafter, attention should be paid to HEV genotype 1 infection as an imported infectious disease.

KW - Acute hepatitis

KW - Genotype

KW - Hepatitis E virus

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Acute hepatitis due to hepatitis e virus genotype 1 as an imported infectious disease in Japan

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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