Adhesive Resin Aiming for Dentin Regeneration

Masahiro Yoshiyama

Research output: Contribution to journalArticlepeer-review


The concept of minimal intervention dentistry has evolved as a consequence of our increased understanding of the caries process and the development of adhesive restorative materials. Recently, new concepts of treatments for dentin caries by use adhesive resins and glass-ionomer cements have been proposed. However, new hard tissue, indicated as the result of applying calcium hydroxide or adhesive resins and/or sterilized by the mixed drugs, formed with a tunnel defect frequency present, running from the medicament interface to pulp. These reports suggest the urgent necessity for us to the establishment of the biological dentin regeneration therapy like the Modified Sealed Restoration (MSR). In this review, we reported “In vivo dentin regeneration by adhesive resin containing EVA+C” and “Future approaches to establish the dentin regeneration therapy”.

Original languageEnglish
Pages (from-to)149-150
Number of pages2
JournalJournal of Hard Tissue Biology
Issue number2
Publication statusPublished - Jan 2005
Externally publishedYes


  • EVA+C
  • dentin regeneration
  • resin adhesion
  • sealed restoration

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry
  • Biomaterials
  • Orthopedics and Sports Medicine
  • General Dentistry
  • Cell Biology


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