TY - GEN
T1 - Adsorption behavior of sodium inositol hexaphosphate on the surface of hydroxyapatite
AU - Konishi, Toshiisa
AU - Mizumoto, Minori
AU - Honda, Michiyo
AU - Aizawa, Mamoru
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - We have previously developed hydroxyapatite (HAp) cement based on the chelate-setting mechanism of sodium inositol hexaphosphate (IP6), in which HAp powder was prepared by surface-modification with IP6 after ball-milling of the HAp powder (conventional process). Meanwhile, we have recently established novel powder preparation process (modified process). In the present study, the adsorption behavior of IP6 on the surface of HAp at both the processes was circumstantially examined to clarify the chelating mechanism of IP6. The adsorbed amount of IP6 increased with the IP6 concentration in both the processes; however, the adsorbed amount of IP6 at the modified process was lower than that at the conventional process. X-ray photoelectron spectroscopic study revealed that the IP6 adsorbed on the surface of HAp powders. The degree in dispersion of the HAp particles at the modified process was higher than that at conventional process. Furthermore, the elution of IP6 from the powders prepared at the novel process was lower than that of the powders at the conventional process.
AB - We have previously developed hydroxyapatite (HAp) cement based on the chelate-setting mechanism of sodium inositol hexaphosphate (IP6), in which HAp powder was prepared by surface-modification with IP6 after ball-milling of the HAp powder (conventional process). Meanwhile, we have recently established novel powder preparation process (modified process). In the present study, the adsorption behavior of IP6 on the surface of HAp at both the processes was circumstantially examined to clarify the chelating mechanism of IP6. The adsorbed amount of IP6 increased with the IP6 concentration in both the processes; however, the adsorbed amount of IP6 at the modified process was lower than that at the conventional process. X-ray photoelectron spectroscopic study revealed that the IP6 adsorbed on the surface of HAp powders. The degree in dispersion of the HAp particles at the modified process was higher than that at conventional process. Furthermore, the elution of IP6 from the powders prepared at the novel process was lower than that of the powders at the conventional process.
KW - Bone graft
KW - Calcium-phosphate cement
KW - Inositol hexaphosphate
KW - Surface modification
UR - http://www.scopus.com/inward/record.url?scp=84871311359&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871311359&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.529-530.161
DO - 10.4028/www.scientific.net/KEM.529-530.161
M3 - Conference contribution
AN - SCOPUS:84871311359
SN - 9783037855171
T3 - Key Engineering Materials
SP - 161
EP - 166
BT - Bioceramics 24
PB - Trans Tech Publications Ltd
T2 - 24th Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2012
Y2 - 21 October 2012 through 24 October 2012
ER -