Adsorption of mutagens to cotton bearing covalently bound trisulfo-copper-phthalocyanine

Hikoya Hayatsu, Takanori Oka, Akihiro Wakata, Yoshiko Ohara, Toshiko Hayatsu, Hiroshi Kobayashi, Sakae Arimoto

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)


A method for separating nonpolar mutagens from their dilute aqueous solutions is described. It utilizes the affinity of the mutagens to a phthalocyanine derivative attached to cotton through a covalent bond. For mutagens having 3 or more fused aromatic rings in their structures, efficient adsorption took place on soaking the cotton in their solutions. The mutagens adsorbed can be recovered by elution with ammoniacal methanol. Mutagenicity in smoker's urine, cooked beef, and river water was detected by use of this method.

Original languageEnglish
Pages (from-to)233-238
Number of pages6
JournalMutation Research Letters
Issue number3-4
Publication statusPublished - Mar 1983

ASJC Scopus subject areas

  • Medicine(all)


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