TY - JOUR
T1 - Adult T‐Cell Leukemia/Lymphoma and Cutaneous T‐Cell Lymphoma Are They Related?
AU - Yamada, Mizuho
AU - Takigawa, M.
AU - Iwatsuki, K.
AU - Inoue, F.
PY - 1989/3
Y1 - 1989/3
N2 - ABSTRACT: Comparative studies were performed on clinical and laboratory features of four patients with different types of T‐cell lymphoma of the skin; adult T‐cell leukemia/lymphoma (ATLL), Sézary syndrome, mycosis fungoides, and Ki‐1‐positive lymphoma. All neoplastic cells studied showed a helper‐inducer T‐cell phenotype. A Ki‐1‐positive lymphoma is distinct from other types of cutaneous lymphomas because of unique morphologic and phenotypic features. Clonal proliferation of lymphocytes infected by human T‐cell lymphotrophic virus (HTLV)‐l distinguishes ATLL from other T‐cell lymphomas of the skin, especially in the endemic area of ATLL. From the pathogeneic point of view, ATLL should not be included in a group with mycosis fungoides and Sezary syndrome.
AB - ABSTRACT: Comparative studies were performed on clinical and laboratory features of four patients with different types of T‐cell lymphoma of the skin; adult T‐cell leukemia/lymphoma (ATLL), Sézary syndrome, mycosis fungoides, and Ki‐1‐positive lymphoma. All neoplastic cells studied showed a helper‐inducer T‐cell phenotype. A Ki‐1‐positive lymphoma is distinct from other types of cutaneous lymphomas because of unique morphologic and phenotypic features. Clonal proliferation of lymphocytes infected by human T‐cell lymphotrophic virus (HTLV)‐l distinguishes ATLL from other T‐cell lymphomas of the skin, especially in the endemic area of ATLL. From the pathogeneic point of view, ATLL should not be included in a group with mycosis fungoides and Sezary syndrome.
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U2 - 10.1111/j.1365-4362.1989.tb01329.x
DO - 10.1111/j.1365-4362.1989.tb01329.x
M3 - Article
C2 - 2786860
AN - SCOPUS:0024565733
SN - 0011-9059
VL - 28
SP - 107
EP - 113
JO - International Journal of Dermatology
JF - International Journal of Dermatology
IS - 2
ER -