Alcohol Consumption and Coronary Artery Calcium in Middle-Aged Japanese Men

Tomonori Okamura, Takashi Kadowaki, Akira Sekikawa, Kiyoshi Murata, Naomi Miyamatsu, Yasuyuki Nakamura, Aiman El-Saed, Atsunori Kashiwagi, Hiroshi Maegawa, Yoshihiko Nishio, Tomoko Takamiya, Hideyuki Kanda, Kenichi Mitsunami, Yoshikuni Kita, Daniel Edmundowicz, Shinji Tamaki, Yasuyuki Tsujita, Lewis H. Kuller, Hirotsugu Ueshima

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


Epidemiologic studies have investigated the relation between alcohol intake and coronary calcification, with controversial results. Furthermore, the influence of heavy drinking has not been well elucidated. In the present study, a random sample of community-based Japanese men aged 40 to 49 years without a history of cardiovascular disease (n = 245) were examined for coronary artery calcium (CAC) determined by electron-beam computed tomography and drinking status. There was a J-shaped association between alcohol intake and CAC. There was an increase of CAC in heavy drinkers (≥46 g/day), and participants who were drinking ≥69 g/day showed a significant increase in CAC compared with never drinkers after adjusting for other cardiovascular risk factors.

Original languageEnglish
Pages (from-to)141-144
Number of pages4
JournalAmerican Journal of Cardiology
Issue number2
Publication statusPublished - Jul 15 2006
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Alcohol Consumption and Coronary Artery Calcium in Middle-Aged Japanese Men'. Together they form a unique fingerprint.

Cite this