An open-label feasibility trial of repetitive transcranial magnetic stimulation for treatment-resistant major depressive episodes

Masaki Fujiwara; Masatoshi Inagaki; Yuji Higuchi; Yosuke Uchitomi; Seishi Terada; Masafumi Kodama; Yoshiki Kishi; Norihito Yamada

An open-label feasibility trial of repetitive transcranial magnetic stimulation for treatment-resistant major depressive episodes

Masaki Fujiwara, Masatoshi Inagaki, Yuji Higuchi, Yosuke Uchitomi, Seishi Terada, Masafumi Kodama, Yoshiki Kishi, Norihito Yamada

Research output: Contribution to journal › Article › peer-review

Abstract

Repetitive transcranial magnetic stimulation (rTMS) has been reported to be a new treatment option for treatment-resistant depression. In Japan, there has been limited research into its feasibility, efficacy, and tolerability. We have launched a trial of rTMS for treating medication-resistant major depressive disorder and bipolar depression. We are investigating low-frequency rTMS to the right dorsolateral prefrontal cortex and traditional high-frequency rTMS to the left dorsolateral prefrontal cortex, in 20 patients. The primary outcome of the study is the treatment completion rate. This study will provide new data on the usefulness of rTMS for treatment-resistant depression in Japan.

Original language	English
Pages (from-to)	307-312
Number of pages	6
Journal	Acta medica Okayama
Volume	70
Issue number	4
Publication status	Published - 2016

Keywords

Depression
Low frequency
Repetitive transcranial magnetic stimulation
Treatment resistance

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

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abstract = "Repetitive transcranial magnetic stimulation (rTMS) has been reported to be a new treatment option for treatment-resistant depression. In Japan, there has been limited research into its feasibility, efficacy, and tolerability. We have launched a trial of rTMS for treating medication-resistant major depressive disorder and bipolar depression. We are investigating low-frequency rTMS to the right dorsolateral prefrontal cortex and traditional high-frequency rTMS to the left dorsolateral prefrontal cortex, in 20 patients. The primary outcome of the study is the treatment completion rate. This study will provide new data on the usefulness of rTMS for treatment-resistant depression in Japan.",

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AU - Higuchi, Yuji

AU - Uchitomi, Yosuke

AU - Terada, Seishi

AU - Kodama, Masafumi

AU - Kishi, Yoshiki

AU - Yamada, Norihito

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AB - Repetitive transcranial magnetic stimulation (rTMS) has been reported to be a new treatment option for treatment-resistant depression. In Japan, there has been limited research into its feasibility, efficacy, and tolerability. We have launched a trial of rTMS for treating medication-resistant major depressive disorder and bipolar depression. We are investigating low-frequency rTMS to the right dorsolateral prefrontal cortex and traditional high-frequency rTMS to the left dorsolateral prefrontal cortex, in 20 patients. The primary outcome of the study is the treatment completion rate. This study will provide new data on the usefulness of rTMS for treatment-resistant depression in Japan.

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An open-label feasibility trial of repetitive transcranial magnetic stimulation for treatment-resistant major depressive episodes

Abstract

Keywords

ASJC Scopus subject areas

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