An Unusual Perpendicular Metallacycle Intermediate is the Origin of Branch Selectivity in the Rh(II)-Catalyzed C-H Alkylation of Aryl Sulfonamides with Vinylsilanes

Physics & Astronomy

• alkylation 100%
• reaction intermediates 91%
• rhodium 78%
• reactivity 60%
• insertion 58%
• selectivity 56%
• density functional theory 46%

Chemical Compounds

• Reaction Intermediate 62%
• Sulfonamide 61%
• Alkylation 51%
• Transition State 49%
• Density Functional Theory 37%