Anaphylaxis after vaccination for cats in Japan

Megumi Yoshida; Keijiro Mizukami; Masaharu Hisasue; Ichiro Imanishi; Keigo Kurata; Masaki Ochiai; Masato Itoh; Tadahiro Nasukawa; Jumpei Uchiyama; Hajime Tsujimoto; Masahiro Sakaguchi

doi:10.1292/jvms.21-0437

Anaphylaxis after vaccination for cats in Japan

Megumi Yoshida, Keijiro Mizukami, Masaharu Hisasue, Ichiro Imanishi, Keigo Kurata, Masaki Ochiai, Masato Itoh, Tadahiro Nasukawa, Jumpei Uchiyama, Hajime Tsujimoto, Masahiro Sakaguchi

Research output: Contribution to journal › Comment/debate › peer-review

1 Citation (Scopus)

Abstract

Severe adverse reactions in cats after vaccination were examined from 316 cases reported to the Ministry of Agriculture, Forestry and Fisheries (MAFF) in Japan during 15-year period from April 2004 to March 2019. We found that 130 (41%) showed anaphylaxis, and 99 (76%) of the 130 cases of anaphylaxis resulted in death. Veterinarians should be well prepared to deal with vaccine-associated anaphylaxis in cats. Bovine serum albumin (BSA) as indicator of purification was detected at high levels in commercially available feline vaccines. BSA might derive from fetal calf serum in culture media. This study provides useful information about anaphylaxis including critical details of the potential clinical signs associated with adverse events to feline vaccination.

Original language	English
Pages (from-to)	149-152
Number of pages	4
Journal	Journal of Veterinary Medical Science
Volume	84
Issue number	1
DOIs	https://doi.org/10.1292/jvms.21-0437
Publication status	Published - Jan 2022
Externally published	Yes

Keywords

Adverse reaction
Anaphylaxis
Bovine serum albumin
Feline vaccine

ASJC Scopus subject areas

veterinary(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1292/jvms.21-0437

Cite this

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title = "Anaphylaxis after vaccination for cats in Japan",

abstract = "Severe adverse reactions in cats after vaccination were examined from 316 cases reported to the Ministry of Agriculture, Forestry and Fisheries (MAFF) in Japan during 15-year period from April 2004 to March 2019. We found that 130 (41%) showed anaphylaxis, and 99 (76%) of the 130 cases of anaphylaxis resulted in death. Veterinarians should be well prepared to deal with vaccine-associated anaphylaxis in cats. Bovine serum albumin (BSA) as indicator of purification was detected at high levels in commercially available feline vaccines. BSA might derive from fetal calf serum in culture media. This study provides useful information about anaphylaxis including critical details of the potential clinical signs associated with adverse events to feline vaccination.",

keywords = "Adverse reaction, Anaphylaxis, Bovine serum albumin, Feline vaccine",

author = "Megumi Yoshida and Keijiro Mizukami and Masaharu Hisasue and Ichiro Imanishi and Keigo Kurata and Masaki Ochiai and Masato Itoh and Tadahiro Nasukawa and Jumpei Uchiyama and Hajime Tsujimoto and Masahiro Sakaguchi",

note = "Funding Information: ACKNOWLEDGMENT. This study was supported by the Ministry of Education, Culture, Sports, Science and Technology-Supported Program for the Private University Research Branding Project, 2016–2020. Publisher Copyright: {\textcopyright} 2022 The Japanese Society of Veterinary Science.",

year = "2022",

month = jan,

doi = "10.1292/jvms.21-0437",

language = "English",

volume = "84",

pages = "149--152",

journal = "Journal of Veterinary Medical Science",

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T1 - Anaphylaxis after vaccination for cats in Japan

AU - Yoshida, Megumi

AU - Mizukami, Keijiro

AU - Hisasue, Masaharu

AU - Imanishi, Ichiro

AU - Kurata, Keigo

AU - Ochiai, Masaki

AU - Itoh, Masato

AU - Nasukawa, Tadahiro

AU - Uchiyama, Jumpei

AU - Tsujimoto, Hajime

AU - Sakaguchi, Masahiro

N1 - Funding Information: ACKNOWLEDGMENT. This study was supported by the Ministry of Education, Culture, Sports, Science and Technology-Supported Program for the Private University Research Branding Project, 2016–2020. Publisher Copyright: © 2022 The Japanese Society of Veterinary Science.

PY - 2022/1

Y1 - 2022/1

N2 - Severe adverse reactions in cats after vaccination were examined from 316 cases reported to the Ministry of Agriculture, Forestry and Fisheries (MAFF) in Japan during 15-year period from April 2004 to March 2019. We found that 130 (41%) showed anaphylaxis, and 99 (76%) of the 130 cases of anaphylaxis resulted in death. Veterinarians should be well prepared to deal with vaccine-associated anaphylaxis in cats. Bovine serum albumin (BSA) as indicator of purification was detected at high levels in commercially available feline vaccines. BSA might derive from fetal calf serum in culture media. This study provides useful information about anaphylaxis including critical details of the potential clinical signs associated with adverse events to feline vaccination.

AB - Severe adverse reactions in cats after vaccination were examined from 316 cases reported to the Ministry of Agriculture, Forestry and Fisheries (MAFF) in Japan during 15-year period from April 2004 to March 2019. We found that 130 (41%) showed anaphylaxis, and 99 (76%) of the 130 cases of anaphylaxis resulted in death. Veterinarians should be well prepared to deal with vaccine-associated anaphylaxis in cats. Bovine serum albumin (BSA) as indicator of purification was detected at high levels in commercially available feline vaccines. BSA might derive from fetal calf serum in culture media. This study provides useful information about anaphylaxis including critical details of the potential clinical signs associated with adverse events to feline vaccination.

KW - Adverse reaction

KW - Anaphylaxis

KW - Bovine serum albumin

KW - Feline vaccine

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U2 - 10.1292/jvms.21-0437

DO - 10.1292/jvms.21-0437

M3 - Comment/debate

C2 - 34789596

AN - SCOPUS:85123814331

SN - 0916-7250

VL - 84

SP - 149

EP - 152

JO - Journal of Veterinary Medical Science

JF - Journal of Veterinary Medical Science

IS - 1

ER -

Anaphylaxis after vaccination for cats in Japan

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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