Anti-demineralization effects of dental adhesive-composites on enamel–root dentin junction

Yu Jung Lai, Rena Takahashi, Po Yen Lin, Ling Kuo, Yuan Zhou, Khairul Matin, Yu Chih Chiang, Yasushi Shimada, Junji Tagami

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Oral biofilm reactor (OBR) and pH cycling (pHC) artificial caries model were employed to evaluate the anti-demineralization effects of four composite filling systems on enamel–root dentin junction. Sixty-four enamel–root dentin blocks (6 mm × 6 mm × 2 mm) each with a cylindrical cavity were randomly assigned to the pHC and OBR group, then four subgroups (n = 8) and filled with either the Beautifil II (BEF, SPRG-filler-containing) or Estelite (EST) composite after the adhesive (either Single Bond Universal (SBU) or FL Bond II (FL, SPRG-filler-containing)). The demineralization lesions of filling interface were examined by micro-computerized tomography (µCT) and swept-sourceoptical coherence tomography (SS-OCT). According to the degree of interface damage, the caries lesions were sorted into four types: Type A and B (no attachment loss); Type C and D (attachment loss). EST/SBU showed the worst demineralization lesion and attachment loss (100% Type D), while BEF/FL exhibited the shallowest lesion depth (p < 0.05, 145 ± 45 µm on enamel, 275 ± 35 µm on root dentin) and no attachment loss (75% Type A and 25% Type B). Using FL adhesive alone does not effectively reduce enamel demineralization. BEF plays a leading role in acid resistance. The combination of BEF and FL showed a cumulative synergistic effect on anti-demineralization.

Original languageEnglish
Article number3327
Issue number19
Publication statusPublished - Oct 1 2021


  • 10-MDP
  • Adhesive composite
  • Micro-CT
  • Oral biofilm reactor
  • SPRG-filler
  • Swept-source-OCT

ASJC Scopus subject areas

  • Chemistry(all)
  • Polymers and Plastics


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