Abstract
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently-discovered autoimmune disorder in which antibodies target NMDAR in the brain. The number of reported cases of anti-NMDAR encephalitis has increased rapidly. Anti-NMDAR encephalitis can be mistakenly diagnosed as psychiatric disorders because many patients present with prominent psychiatric symptoms and visit psychiatric institutions first. Thus, psychiatrists should cultivate a better understanding of anti-NMDAR encephalitis. In this review, we present the mechanisms, epidemiology, symptoms and clinical course, diagnostic tests, treatment and outcomes of patients with anti-NMDAR encephalitis. Furthermore, we discuss the diversity of clinical spectra of anti- NMDAR encephalitis, and demonstrate a differential diagnosis of psychiatric disease from the perspective of psychiatry.
| Original language | English |
|---|---|
| Pages (from-to) | 189-195 |
| Number of pages | 7 |
| Journal | Acta medica Okayama |
| Volume | 73 |
| Issue number | 3 |
| Publication status | Published - 2019 |
Keywords
- Encephalitis
- Mood disorder
- NMDAR
- Psychiatric symptom
- Schizophrenia
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)