Antibody Response to Oral Streptococci in Behcet's Disease

Kenji Yokota; Syunii Hayashi; Nobuhiro Fujii; Kouji Yoshikawa; Satoshi Kotake; Emiko Isogai; Shigeaki Ohno; Yoshio Araki; Keiji Oguma

doi:10.1111/j.1348-0421.1992.tb02083.x

Antibody Response to Oral Streptococci in Behcet's Disease

Kenji Yokota, Syunii Hayashi, Nobuhiro Fujii, Kouji Yoshikawa, Satoshi Kotake, Emiko Isogai, Shigeaki Ohno, Yoshio Araki, Keiji Oguma

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

The serum antibody titers against oral streptococci were studied by enzyme-linked immunosorbent assay (ELISA) both in patients with Behcet's disease (BD) and control groups. The patients with BD showed significantly higher antibody titers to S. sanguis strains 113–20, 114–23, and 118–1 which were isolated from patients with BD, in comparison with control groups. Also, the reactions of high-titered sera to the crude cell wall and soluble (or membrane) fractions of the 113–20 strain were observed by western blot test. The sera of the patients with BD demonstrated strong bands of approximately 36 kDa, 82 kDa, and 87 kDa in the crude cell wall fractions, and many bands of 80 kDa to 150 kDa in the membrane fractions, indicating that these proteins are the ones leading the high antibody titers to this bacterium in the sera of patients with BD.

Original language	English
Pages (from-to)	815-822
Number of pages	8
Journal	MICROBIOLOGY and IMMUNOLOGY
Volume	36
Issue number	8
DOIs	https://doi.org/10.1111/j.1348-0421.1992.tb02083.x
Publication status	Published - 1992

ASJC Scopus subject areas

Microbiology
Immunology
Virology

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10.1111/j.1348-0421.1992.tb02083.x

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title = "Antibody Response to Oral Streptococci in Behcet's Disease",

abstract = "The serum antibody titers against oral streptococci were studied by enzyme-linked immunosorbent assay (ELISA) both in patients with Behcet's disease (BD) and control groups. The patients with BD showed significantly higher antibody titers to S. sanguis strains 113–20, 114–23, and 118–1 which were isolated from patients with BD, in comparison with control groups. Also, the reactions of high-titered sera to the crude cell wall and soluble (or membrane) fractions of the 113–20 strain were observed by western blot test. The sera of the patients with BD demonstrated strong bands of approximately 36 kDa, 82 kDa, and 87 kDa in the crude cell wall fractions, and many bands of 80 kDa to 150 kDa in the membrane fractions, indicating that these proteins are the ones leading the high antibody titers to this bacterium in the sera of patients with BD.",

author = "Kenji Yokota and Syunii Hayashi and Nobuhiro Fujii and Kouji Yoshikawa and Satoshi Kotake and Emiko Isogai and Shigeaki Ohno and Yoshio Araki and Keiji Oguma",

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T1 - Antibody Response to Oral Streptococci in Behcet's Disease

AU - Yokota, Kenji

AU - Hayashi, Syunii

AU - Fujii, Nobuhiro

AU - Yoshikawa, Kouji

AU - Kotake, Satoshi

AU - Isogai, Emiko

AU - Ohno, Shigeaki

AU - Araki, Yoshio

AU - Oguma, Keiji

PY - 1992

Y1 - 1992

N2 - The serum antibody titers against oral streptococci were studied by enzyme-linked immunosorbent assay (ELISA) both in patients with Behcet's disease (BD) and control groups. The patients with BD showed significantly higher antibody titers to S. sanguis strains 113–20, 114–23, and 118–1 which were isolated from patients with BD, in comparison with control groups. Also, the reactions of high-titered sera to the crude cell wall and soluble (or membrane) fractions of the 113–20 strain were observed by western blot test. The sera of the patients with BD demonstrated strong bands of approximately 36 kDa, 82 kDa, and 87 kDa in the crude cell wall fractions, and many bands of 80 kDa to 150 kDa in the membrane fractions, indicating that these proteins are the ones leading the high antibody titers to this bacterium in the sera of patients with BD.

AB - The serum antibody titers against oral streptococci were studied by enzyme-linked immunosorbent assay (ELISA) both in patients with Behcet's disease (BD) and control groups. The patients with BD showed significantly higher antibody titers to S. sanguis strains 113–20, 114–23, and 118–1 which were isolated from patients with BD, in comparison with control groups. Also, the reactions of high-titered sera to the crude cell wall and soluble (or membrane) fractions of the 113–20 strain were observed by western blot test. The sera of the patients with BD demonstrated strong bands of approximately 36 kDa, 82 kDa, and 87 kDa in the crude cell wall fractions, and many bands of 80 kDa to 150 kDa in the membrane fractions, indicating that these proteins are the ones leading the high antibody titers to this bacterium in the sera of patients with BD.

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Antibody Response to Oral Streptococci in Behcet's Disease

Abstract

ASJC Scopus subject areas

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