Antifungal drugs effect adherence of Candida albicans to acrylic surfaces by changing the zeta-potential of fungal cells

Yoichiro Miyake; Tatsuhiko Tsunoda; Shogo Minagi; Yasumasa Akagawa; Hiromichi Tsuru; Hidekazu Suginaka

doi:10.1016/0378-1097(90)90067-Z

Antifungal drugs effect adherence of Candida albicans to acrylic surfaces by changing the zeta-potential of fungal cells

Yoichiro Miyake, Tatsuhiko Tsunoda, Shogo Minagi, Yasumasa Akagawa, Hiromichi Tsuru, Hidekazu Suginaka

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

The effect of sub-inhibitory concentrations of antifungal drugs on the adherence of Candida albicans to acrylic surfaces was investigated. Among five antifungals tested, azalomycin F and aculeacin A significantly enhanced the adherence. The zeta-potential of fungal cells was affected by antifungal drugs, whereas no significant change in cell surface hydrophobicity was observed. The relationship obtained between the change in the adherence and that in zeta-potential suggests that the enhanced adherence was caused by decreased electric repulsive forces.

Original language	English
Pages (from-to)	211-214
Number of pages	4
Journal	FEMS Microbiology Letters
Volume	69
Issue number	3
DOIs	https://doi.org/10.1016/0378-1097(90)90067-Z
Publication status	Published - Jun 1 1990
Externally published	Yes

Keywords

Acrylic resin
Adherence
Antifungal drug
Candida albicans
Zeta-potenital

ASJC Scopus subject areas

Microbiology
Molecular Biology
Genetics

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10.1016/0378-1097(90)90067-Z

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title = "Antifungal drugs effect adherence of Candida albicans to acrylic surfaces by changing the zeta-potential of fungal cells",

abstract = "The effect of sub-inhibitory concentrations of antifungal drugs on the adherence of Candida albicans to acrylic surfaces was investigated. Among five antifungals tested, azalomycin F and aculeacin A significantly enhanced the adherence. The zeta-potential of fungal cells was affected by antifungal drugs, whereas no significant change in cell surface hydrophobicity was observed. The relationship obtained between the change in the adherence and that in zeta-potential suggests that the enhanced adherence was caused by decreased electric repulsive forces.",

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AU - Miyake, Yoichiro

AU - Tsunoda, Tatsuhiko

AU - Minagi, Shogo

AU - Akagawa, Yasumasa

AU - Tsuru, Hiromichi

AU - Suginaka, Hidekazu

PY - 1990/6/1

Y1 - 1990/6/1

N2 - The effect of sub-inhibitory concentrations of antifungal drugs on the adherence of Candida albicans to acrylic surfaces was investigated. Among five antifungals tested, azalomycin F and aculeacin A significantly enhanced the adherence. The zeta-potential of fungal cells was affected by antifungal drugs, whereas no significant change in cell surface hydrophobicity was observed. The relationship obtained between the change in the adherence and that in zeta-potential suggests that the enhanced adherence was caused by decreased electric repulsive forces.

AB - The effect of sub-inhibitory concentrations of antifungal drugs on the adherence of Candida albicans to acrylic surfaces was investigated. Among five antifungals tested, azalomycin F and aculeacin A significantly enhanced the adherence. The zeta-potential of fungal cells was affected by antifungal drugs, whereas no significant change in cell surface hydrophobicity was observed. The relationship obtained between the change in the adherence and that in zeta-potential suggests that the enhanced adherence was caused by decreased electric repulsive forces.

KW - Acrylic resin

KW - Adherence

KW - Antifungal drug

KW - Candida albicans

KW - Zeta-potenital

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Antifungal drugs effect adherence of Candida albicans to acrylic surfaces by changing the zeta-potential of fungal cells

Abstract

Keywords

ASJC Scopus subject areas

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