Antioxidative properties of functional polyphenols and their metabolites assessed by an ORAC assay

Hidekazu Ishimoto; Akihiro Tai; Morio Yoshimura; Yoshiaki Amakura; Takashi Yoshida; Tsutomu Hatano; Hideyuki Ito

doi:10.1271/bbb.110717

Antioxidative properties of functional polyphenols and their metabolites assessed by an ORAC assay

Hidekazu Ishimoto, Akihiro Tai, Morio Yoshimura, Yoshiaki Amakura, Takashi Yoshida, Tsutomu Hatano, Hideyuki Ito

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Abstract

We compared the antioxidative activities of polyphenol metabolites with those of intact functional polyphenols by an assay of the oxygen radical absorbance capacity (ORAC). The metabolites of ellagitannin geraniin, chlorogenic acid, and (-)-epigallocatechin gallate displayed more potent antioxidative activity than their respective original compounds. Our findings suggest that these metabolites may play important roles as biological antioxidants after their consumption.

Original language	English
Pages (from-to)	395-399
Number of pages	5
Journal	Bioscience, Biotechnology and Biochemistry
Volume	76
Issue number	2
DOIs	https://doi.org/10.1271/bbb.110717
Publication status	Published - 2012

Keywords

AAPH
Antioxidative activity
Metabolite
Oxygen radical absorbance capacity (ORAC)
Polyphenol

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

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10.1271/bbb.110717

Cite this

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title = "Antioxidative properties of functional polyphenols and their metabolites assessed by an ORAC assay",

abstract = "We compared the antioxidative activities of polyphenol metabolites with those of intact functional polyphenols by an assay of the oxygen radical absorbance capacity (ORAC). The metabolites of ellagitannin geraniin, chlorogenic acid, and (-)-epigallocatechin gallate displayed more potent antioxidative activity than their respective original compounds. Our findings suggest that these metabolites may play important roles as biological antioxidants after their consumption.",

keywords = "AAPH, Antioxidative activity, Metabolite, Oxygen radical absorbance capacity (ORAC), Polyphenol",

author = "Hidekazu Ishimoto and Akihiro Tai and Morio Yoshimura and Yoshiaki Amakura and Takashi Yoshida and Tsutomu Hatano and Hideyuki Ito",

note = "Funding Information: This study was supported in part by grant aid for scientific research (no. 17604005) from the Ministry of Education, Culture, Sports, Science, and Technology of Japan. We thank Dr. Toshiyuki Fukuda for providing (−)-epigallocatechin 3-O-(300-O-methyl)gallate.",

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doi = "10.1271/bbb.110717",

language = "English",

volume = "76",

pages = "395--399",

journal = "Bioscience, Biotechnology and Biochemistry",

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T1 - Antioxidative properties of functional polyphenols and their metabolites assessed by an ORAC assay

AU - Ishimoto, Hidekazu

AU - Tai, Akihiro

AU - Yoshimura, Morio

AU - Amakura, Yoshiaki

AU - Yoshida, Takashi

AU - Hatano, Tsutomu

AU - Ito, Hideyuki

N1 - Funding Information: This study was supported in part by grant aid for scientific research (no. 17604005) from the Ministry of Education, Culture, Sports, Science, and Technology of Japan. We thank Dr. Toshiyuki Fukuda for providing (−)-epigallocatechin 3-O-(300-O-methyl)gallate.

PY - 2012

Y1 - 2012

N2 - We compared the antioxidative activities of polyphenol metabolites with those of intact functional polyphenols by an assay of the oxygen radical absorbance capacity (ORAC). The metabolites of ellagitannin geraniin, chlorogenic acid, and (-)-epigallocatechin gallate displayed more potent antioxidative activity than their respective original compounds. Our findings suggest that these metabolites may play important roles as biological antioxidants after their consumption.

AB - We compared the antioxidative activities of polyphenol metabolites with those of intact functional polyphenols by an assay of the oxygen radical absorbance capacity (ORAC). The metabolites of ellagitannin geraniin, chlorogenic acid, and (-)-epigallocatechin gallate displayed more potent antioxidative activity than their respective original compounds. Our findings suggest that these metabolites may play important roles as biological antioxidants after their consumption.

KW - AAPH

KW - Antioxidative activity

KW - Metabolite

KW - Oxygen radical absorbance capacity (ORAC)

KW - Polyphenol

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Antioxidative properties of functional polyphenols and their metabolites assessed by an ORAC assay

Abstract

Keywords

ASJC Scopus subject areas

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