Asymmetric expression of antivin/lefty1 in the early chick embryo

Yoshiyasu Ishimaru, Hidefumi Yoshioka, Hirotaka Tao, Bernard Thisse, Christine Thisse, Christopher V.E. Wright, Hiroshi Hamada, Hideyo Ohuchi, Sumihare Noji

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)


Mammalian lefty and zebrafish antivin, highly related to lefty, are shown to be expressed asymmetrically and involved in the specification of the left body side of early embryos. We isolated a chick homologue of the antivin/lefty1 cDNA and studied its expression pattern during early chick development. We found that antivin/lefty1 is expressed asymmetrically on the left side of the prospective floorplate, notochord and lateral plate mesoderm of the chick embryo. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)115-118
Number of pages4
JournalMechanisms of Development
Issue number1
Publication statusPublished - Jan 1 2000
Externally publishedYes


  • Chick embryo
  • Lateral plate mesoderm
  • Left-right asymmetry
  • Notochord
  • Prospective floorplate
  • TGFβ
  • antivin
  • lefty1

ASJC Scopus subject areas

  • Embryology
  • Developmental Biology


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