Asymmetric Synthesis of Substituted Isoxazolidinone from α,β-Unsaturated Esters and Hydroxylamines by means of Double Stereodifferentiation

Teruhiko Ishikawa; Keita Nagai; Takayuki Kudoh; Seiki Saito

doi:10.1055/s-1995-5228

Asymmetric Synthesis of Substituted Isoxazolidinone from α,β-Unsaturated Esters and Hydroxylamines by means of Double Stereodifferentiation

Teruhiko Ishikawa, Keita Nagai, Takayuki Kudoh, Seiki Saito

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Asymmetric synthesis of isoxazolidinones (1) has been developed by Michael addition and ensuing transesterification processes employing chiral hydroxylamines and α,β-unsaturated esters carrying chiral α-hydroxycarboxylic acid ester unit as an alkoxide moiety.

Original language	English
Pages (from-to)	1171-1173
Number of pages	3
Journal	Synlett
Volume	1995
Issue number	11
DOIs	https://doi.org/10.1055/s-1995-5228
Publication status	Published - Nov 1995

Keywords

Chiral hydroxylamine
Double Stereodifferentiation
Isoxazolidinone
Michael addition
β-Amino acid synthon

ASJC Scopus subject areas

Organic Chemistry

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title = "Asymmetric Synthesis of Substituted Isoxazolidinone from α,β-Unsaturated Esters and Hydroxylamines by means of Double Stereodifferentiation",

abstract = "Asymmetric synthesis of isoxazolidinones (1) has been developed by Michael addition and ensuing transesterification processes employing chiral hydroxylamines and α,β-unsaturated esters carrying chiral α-hydroxycarboxylic acid ester unit as an alkoxide moiety.",

keywords = "Chiral hydroxylamine, Double Stereodifferentiation, Isoxazolidinone, Michael addition, β-Amino acid synthon",

author = "Teruhiko Ishikawa and Keita Nagai and Takayuki Kudoh and Seiki Saito",

year = "1995",

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doi = "10.1055/s-1995-5228",

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AU - Ishikawa, Teruhiko

AU - Nagai, Keita

AU - Kudoh, Takayuki

AU - Saito, Seiki

PY - 1995/11

Y1 - 1995/11

N2 - Asymmetric synthesis of isoxazolidinones (1) has been developed by Michael addition and ensuing transesterification processes employing chiral hydroxylamines and α,β-unsaturated esters carrying chiral α-hydroxycarboxylic acid ester unit as an alkoxide moiety.

AB - Asymmetric synthesis of isoxazolidinones (1) has been developed by Michael addition and ensuing transesterification processes employing chiral hydroxylamines and α,β-unsaturated esters carrying chiral α-hydroxycarboxylic acid ester unit as an alkoxide moiety.

KW - Chiral hydroxylamine

KW - Double Stereodifferentiation

KW - Isoxazolidinone

KW - Michael addition

KW - β-Amino acid synthon

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DO - 10.1055/s-1995-5228

M3 - Article

AN - SCOPUS:0002783698

SN - 0936-5214

VL - 1995

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ER -

Asymmetric Synthesis of Substituted Isoxazolidinone from α,β-Unsaturated Esters and Hydroxylamines by means of Double Stereodifferentiation

Abstract

Keywords

ASJC Scopus subject areas

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