Automatic measurement system for biological applications based on pH using ISFET sensor probe

Akira Yamada; Satoshi Mohri; Michihiro Nakamura; Keiji Naruse

doi:10.1109/MHS.2010.5669583

Automatic measurement system for biological applications based on pH using ISFET sensor probe

Akira Yamada, Satoshi Mohri, Michihiro Nakamura, Keiji Naruse

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Throughput in the cell response analysis is expected to progress in medicine and biology. In this paper, we construct a method for the measurement of cell activity that is measured by the pH fluctuation of the solution around the cell. To improve throughput of the measurements, first we constructed an automatic pH measurement system using ion-sensitive field-effect transistor (ISFET), and the system composed of 96-well microplate, pump, XYZ stage, and PC. The basic data of the cell activity was taken from human embryonic kidney 293 (HEK 293) cells by the use of flow-through type measuring chamber.

Original language	English
Title of host publication	2010 International Symposium on Micro-NanoMechatronics and Human Science
Subtitle of host publication	From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010
Pages	19-24
Number of pages	6
DOIs	https://doi.org/10.1109/MHS.2010.5669583
Publication status	Published - 2010
Event	21st Annual Symposium on Micro-Nano Mechatronics and Human Science, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010 - Nagoya, Japan Duration: Nov 7 2010 → Nov 10 2010

Publication series

Name	2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010

Other

Other	21st Annual Symposium on Micro-Nano Mechatronics and Human Science, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010
Country/Territory	Japan
City	Nagoya
Period	11/7/10 → 11/10/10

ASJC Scopus subject areas

Electrical and Electronic Engineering
Mechanical Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1109/MHS.2010.5669583

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Yamada, A., Mohri, S., Nakamura, M., & Naruse, K. (2010). Automatic measurement system for biological applications based on pH using ISFET sensor probe. In 2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010 (pp. 19-24). [5669583] (2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010). https://doi.org/10.1109/MHS.2010.5669583

Automatic measurement system for biological applications based on pH using ISFET sensor probe. / Yamada, Akira; Mohri, Satoshi; Nakamura, Michihiro et al.
2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010. 2010. p. 19-24 5669583 (2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Yamada, A, Mohri, S, Nakamura, M & Naruse, K 2010, Automatic measurement system for biological applications based on pH using ISFET sensor probe. in 2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010., 5669583, 2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010, pp. 19-24, 21st Annual Symposium on Micro-Nano Mechatronics and Human Science, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010, Nagoya, Japan, 11/7/10. https://doi.org/10.1109/MHS.2010.5669583

Yamada A, Mohri S, Nakamura M, Naruse K. Automatic measurement system for biological applications based on pH using ISFET sensor probe. In 2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010. 2010. p. 19-24. 5669583. (2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010). doi: 10.1109/MHS.2010.5669583

Yamada, Akira ; Mohri, Satoshi ; Nakamura, Michihiro et al. / Automatic measurement system for biological applications based on pH using ISFET sensor probe. 2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010. 2010. pp. 19-24 (2010 International Symposium on Micro-NanoMechatronics and Human Science: From Micro and Nano Scale Systems to Robotics and Mechatronics Systems, MHS 2010, Micro-Nano GCOE 2010, Bio-Manipulation 2010).

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abstract = "Throughput in the cell response analysis is expected to progress in medicine and biology. In this paper, we construct a method for the measurement of cell activity that is measured by the pH fluctuation of the solution around the cell. To improve throughput of the measurements, first we constructed an automatic pH measurement system using ion-sensitive field-effect transistor (ISFET), and the system composed of 96-well microplate, pump, XYZ stage, and PC. The basic data of the cell activity was taken from human embryonic kidney 293 (HEK 293) cells by the use of flow-through type measuring chamber.",

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Automatic measurement system for biological applications based on pH using ISFET sensor probe

Abstract

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ASJC Scopus subject areas

UN SDGs

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