Balloon aortic valvuloplasty in children: A multicenter study in Japan

H. Tomita, S. Echigo, K. Kimura, T. Kobayashi, T. Nakanishi, R. Ishizawa, T. Akagi, T. Ino, Y. Harada, H. Kado, T. Yagihara

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


A questionnaire was used to survey the experience of 8 Japanese institutions with percutaneous transluminal aortic valvuloplasty (PTAV) in children. Among 99 procedures reported in 88 p-tients, sufficient data for analysis was obtained from 76 procedures in 72 patients. In those 76 procedures the pressure gradient decreased significantly from 68±25 (20-140) to 33±22 (0- 100) mmHg (p<0.01), whereas aortic regurgitation (AR) increased at least one grade in 26 cases (34%). None of the parameters analyzed in this study were predictors of an increase in AR. The reduction in pressure gradient was judged as good in 44 of the 76 procedures (58%). A larger ring diameter, larger balloon diameter and larger ratio balloon diameter/the normal predicted diameter of the aortic valve ring significantly contributed to an effective reduction of pressure gradient. Follow up data (mean interval, 4 years) was available for 26 of 39 clinically effective procedures. AR progressed at least 1 grade in 11 (42%), and the pressure gradient re-developed to more than 50 mmHg in 2 cases (8%). In Japan, PTAV has been accepted as a useful procedure for valvular aortic stenosis in children, but progressive AR or re-development of the pressure gradient is not uncommon even after clinically effective PTAV.

Original languageEnglish
Pages (from-to)599-602
Number of pages4
Issue number7
Publication statusPublished - 2001
Externally publishedYes


  • Balloon aortic valvuloplasty
  • Pediatrics
  • Valvular aortic stenosis

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine


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