Basicity of N-Terminal amine in ATCUN peptide regulates stability constant of albumin-like Cu2+ complex

Takaaki Miyamoto; Shinichiro Kamino; Akira Odani; Makoto Hiromura; Shuichi Enomoto

doi:10.1246/cl.130405

Basicity of N-Terminal amine in ATCUN peptide regulates stability constant of albumin-like Cu2+ complex

Takaaki Miyamoto, Shinichiro Kamino, Akira Odani, Makoto Hiromura, Shuichi Enomoto

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

We quantitatively investigated the coordination ability of ATCUN peptides possessing various amino acid residues on the N-terminal side of the third histidine, toward Cu2+. We discovered that the stability of the Cu2+ATCUN complex was governed by the acidity of the N-terminal amino nitrogen in the peptides.

Original language	English
Pages (from-to)	1099-1101
Number of pages	3
Journal	Chemistry Letters
Volume	42
Issue number	9
DOIs	https://doi.org/10.1246/cl.130405
Publication status	Published - 2013

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.130405

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title = "Basicity of N-Terminal amine in ATCUN peptide regulates stability constant of albumin-like Cu2+ complex",

abstract = "We quantitatively investigated the coordination ability of ATCUN peptides possessing various amino acid residues on the N-terminal side of the third histidine, toward Cu2+. We discovered that the stability of the Cu2+ATCUN complex was governed by the acidity of the N-terminal amino nitrogen in the peptides.",

author = "Takaaki Miyamoto and Shinichiro Kamino and Akira Odani and Makoto Hiromura and Shuichi Enomoto",

year = "2013",

doi = "10.1246/cl.130405",

language = "English",

volume = "42",

pages = "1099--1101",

journal = "Chemistry Letters",

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publisher = "Chemical Society of Japan",

number = "9",

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TY - JOUR

T1 - Basicity of N-Terminal amine in ATCUN peptide regulates stability constant of albumin-like Cu2+ complex

AU - Miyamoto, Takaaki

AU - Kamino, Shinichiro

AU - Odani, Akira

AU - Hiromura, Makoto

AU - Enomoto, Shuichi

PY - 2013

Y1 - 2013

N2 - We quantitatively investigated the coordination ability of ATCUN peptides possessing various amino acid residues on the N-terminal side of the third histidine, toward Cu2+. We discovered that the stability of the Cu2+ATCUN complex was governed by the acidity of the N-terminal amino nitrogen in the peptides.

AB - We quantitatively investigated the coordination ability of ATCUN peptides possessing various amino acid residues on the N-terminal side of the third histidine, toward Cu2+. We discovered that the stability of the Cu2+ATCUN complex was governed by the acidity of the N-terminal amino nitrogen in the peptides.

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U2 - 10.1246/cl.130405

DO - 10.1246/cl.130405

M3 - Article

AN - SCOPUS:84883724433

SN - 0366-7022

VL - 42

SP - 1099

EP - 1101

JO - Chemistry Letters

JF - Chemistry Letters

IS - 9

ER -

Basicity of N-Terminal amine in ATCUN peptide regulates stability constant of albumin-like Cu2+ complex

Abstract

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