Biomimetic deposition of apatite on electrochemically oxidized titanium substrates

A. Osaka, X. X. Wang, S. Hayakawa, K. Tsuru

Research output: Contribution to journalConference articlepeer-review

3 Citations (Scopus)


Apatite formation on artificial materials in a body environment is prerequisite for bioactivity or tissue-material bonding. A specific hydrated silica or titania gel has the ability of apatite deposition in body environment. Electrochemical preparation of such a bioactive titanium oxide layer on titanium (Ti) is reported. Ti was kept at 9.5 V for 1 hour for oxidation and subsequently kept at -2.0 V for 10 min for adsorbing calcium hydroxide on the surface. The specimens subject to the electrochemical treatments were found so bioactive as to deposit apatite within 12 hours in a simulated body fluid. Calcium hydroxide precipitated on the bioactive surface favored spontaneous deposition of apatite in the fluid. We examined the effect of autoclave sterilization considered in vivo experiment. It slightly reduced the ability of apatite deposition.

Original languageEnglish
Pages (from-to)263-266
Number of pages4
JournalKey Engineering Materials
Publication statusPublished - 2001
Event13th international Symposium on Ceramics in Medicine (BIOCERAMICS) - Bologna, Italy
Duration: Nov 22 2000Nov 26 2000

ASJC Scopus subject areas

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering


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