TY - JOUR
T1 - Blood flow patterns in the rat pancreas
T2 - A simulative demonstration by injection replication and scanning electron microscopy
AU - Murakami, Takuro
AU - Miyake, Tsuyoshi
AU - Tsubouchi, Mari
AU - Tsubouchi, Yutaka
AU - Ohtsuka, Aiji
AU - Fujita, Tsuneo
PY - 1997/6/1
Y1 - 1997/6/1
N2 - Scanning electron microscopy of vascular casts prepared by arterial injections of intentionally reduced amounts of resin showed that in the rat pancreas, the casting medium fills blood capillaries in the endocrine islets more promptly than those in the exocrine lobules and secretory ducts. Furthermore, the exocrine lobules containing endocrine islets allowed a more rapid resin flow through the insulo-acinar portal route than those lobules lacking an islet. The capillaries of secretory ducts were the last portions to be filled with resin. Since the resin used in this study was as viscous as blood and injected under a physiological pressure, the microcirculatory patterns demonstrated by the present method reflect the physiological flow pattern of blood in the pancreas.
AB - Scanning electron microscopy of vascular casts prepared by arterial injections of intentionally reduced amounts of resin showed that in the rat pancreas, the casting medium fills blood capillaries in the endocrine islets more promptly than those in the exocrine lobules and secretory ducts. Furthermore, the exocrine lobules containing endocrine islets allowed a more rapid resin flow through the insulo-acinar portal route than those lobules lacking an islet. The capillaries of secretory ducts were the last portions to be filled with resin. Since the resin used in this study was as viscous as blood and injected under a physiological pressure, the microcirculatory patterns demonstrated by the present method reflect the physiological flow pattern of blood in the pancreas.
KW - Corrosion casting
KW - Microcirculation
KW - Microvascular architecture
KW - Pancreas
KW - Scanning electron microscopy
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U2 - 10.1002/(SICI)1097-0029(19970601)37:5/6<497::AID-JEMT12>3.0.CO;2-L
DO - 10.1002/(SICI)1097-0029(19970601)37:5/6<497::AID-JEMT12>3.0.CO;2-L
M3 - Article
C2 - 9220427
AN - SCOPUS:0030745678
SN - 1059-910X
VL - 37
SP - 497
EP - 508
JO - Microscopy Research and Technique
JF - Microscopy Research and Technique
IS - 5-6
ER -