Brain-gut induction of heat shock protein (HSP) 70 mRNA by psychophysiological stress in rats

Shin Fukudo; Koji Abe; Michio Hongo; Atsushi Utsumi; Yasuto Itoyama

doi:10.1016/S0006-8993(97)00179-0

Brain-gut induction of heat shock protein (HSP) 70 mRNA by psychophysiological stress in rats

Shin Fukudo, Koji Abe, Michio Hongo, Atsushi Utsumi, Yasuto Itoyama

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Restraint water-immersion stress-induced expression of heat shock protein (HSP)70 mRNA in the cerebral cortex and stomach of rats was evaluated by Northern blotting. Cerebral and gastric HSP70 mRNA significantly increased in the 6 h-stressed rats and the amount of mRNA measured as optical densities was highest in the 12 h-stressed rats. These data confirmed our previous observations and suggest that families of HSPs play a salient cytoprotective role in stress-vulnerable organs.

Original language	English
Pages (from-to)	146-148
Number of pages	3
Journal	Brain Research
Volume	757
Issue number	1
DOIs	https://doi.org/10.1016/S0006-8993(97)00179-0
Publication status	Published - May 16 1997
Externally published	Yes

Keywords

Cerebral cortex
Heat shock protein (HSP)70
Messenger RNA
Northern blotting
Rat
Restraint water-immersion stress
Stomach

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/S0006-8993(97)00179-0

Cite this

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title = "Brain-gut induction of heat shock protein (HSP) 70 mRNA by psychophysiological stress in rats",

abstract = "Restraint water-immersion stress-induced expression of heat shock protein (HSP)70 mRNA in the cerebral cortex and stomach of rats was evaluated by Northern blotting. Cerebral and gastric HSP70 mRNA significantly increased in the 6 h-stressed rats and the amount of mRNA measured as optical densities was highest in the 12 h-stressed rats. These data confirmed our previous observations and suggest that families of HSPs play a salient cytoprotective role in stress-vulnerable organs.",

keywords = "Cerebral cortex, Heat shock protein (HSP)70, Messenger RNA, Northern blotting, Rat, Restraint water-immersion stress, Stomach",

author = "Shin Fukudo and Koji Abe and Michio Hongo and Atsushi Utsumi and Yasuto Itoyama",

note = "Funding Information: This work was supported by Grant-in-Aid for Scientific Research from the Ministry of Education, Science, and Culture of Japan.",

year = "1997",

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doi = "10.1016/S0006-8993(97)00179-0",

language = "English",

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T1 - Brain-gut induction of heat shock protein (HSP) 70 mRNA by psychophysiological stress in rats

AU - Fukudo, Shin

AU - Abe, Koji

AU - Hongo, Michio

AU - Utsumi, Atsushi

AU - Itoyama, Yasuto

N1 - Funding Information: This work was supported by Grant-in-Aid for Scientific Research from the Ministry of Education, Science, and Culture of Japan.

PY - 1997/5/16

Y1 - 1997/5/16

N2 - Restraint water-immersion stress-induced expression of heat shock protein (HSP)70 mRNA in the cerebral cortex and stomach of rats was evaluated by Northern blotting. Cerebral and gastric HSP70 mRNA significantly increased in the 6 h-stressed rats and the amount of mRNA measured as optical densities was highest in the 12 h-stressed rats. These data confirmed our previous observations and suggest that families of HSPs play a salient cytoprotective role in stress-vulnerable organs.

AB - Restraint water-immersion stress-induced expression of heat shock protein (HSP)70 mRNA in the cerebral cortex and stomach of rats was evaluated by Northern blotting. Cerebral and gastric HSP70 mRNA significantly increased in the 6 h-stressed rats and the amount of mRNA measured as optical densities was highest in the 12 h-stressed rats. These data confirmed our previous observations and suggest that families of HSPs play a salient cytoprotective role in stress-vulnerable organs.

KW - Cerebral cortex

KW - Heat shock protein (HSP)70

KW - Messenger RNA

KW - Northern blotting

KW - Rat

KW - Restraint water-immersion stress

KW - Stomach

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Brain-gut induction of heat shock protein (HSP) 70 mRNA by psychophysiological stress in rats

Abstract

Keywords

ASJC Scopus subject areas

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