Calcein leakage behavior from vesicles induced by proteinvesicle interaction: A study by surface pressurearea isotherms

Saki Fukuma, Toshinori Shimanouchi, Keita Hayashi, Yukitaka Kimura

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)

    Abstract

    The release behavior of substrates encapsulated in the vesicle can be controlled by the interaction between the vesicular membrane and the protein. However, its control mechanism is still now unknown. Therefore, the proteinvesicle interaction was investigated by a A isotherm. It was clarified that the released amount of encapsulated substrates increased with increasing proteinvesicle interaction. This result leads to the development of drug delivery systems (DDS) and of biosensor technology.

    Original languageEnglish
    Pages (from-to)1036-1039
    Number of pages4
    JournalChemistry Letters
    Volume46
    Issue number7
    DOIs
    Publication statusPublished - 2017

    Keywords

    • Calcein leakage
    • Protein
    • Vesicle

    ASJC Scopus subject areas

    • General Chemistry

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