Can pemphigus vulgaris become pemphigus foliaceus?

Keiji Iwatsuki, Masahiro Takigawa, Takashi Hashimoto, Takeji Nishikawa, Mizuho Yamada

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)


Among 31 patients with pemphigus, we observed two women with clinical and histologic features characteristic of pemphigus vulgaris that later became those of pemphigus foliaceus. Western blot study indicated that serum from one patient, when she had the cutaneous manifestations of pemphigus foliaceus, contained antibodies reactive with a desmosomal antigen, suggestive of desmoglein 1, the same as recognized by pemphigus foliaceus serum. The present study suggests that two distinct types of pemphigus can occur in the same person simultaneously or separately.

Original languageEnglish
Pages (from-to)797-800
Number of pages4
JournalJournal of the American Academy of Dermatology
Issue number5
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Dermatology


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