TY - JOUR
T1 - Cancer stem cell research
T2 - Current situation and problems
AU - Kobayashi, Naoya
AU - Navarro-Alvarez, Nalú
AU - Soto-Gutierrez, Alejandro
AU - Kawamoto, Hironobu
AU - Kondo, Yoshitaka
AU - Yamatsuji, Tomoki
AU - Shirakawa, Yasuhiro
AU - Naomoto, Yoshio
AU - Tanaka, Noriaki
PY - 2008
Y1 - 2008
N2 - The concept of a "cancer stem cell system" that continues to supply cancer component cells has been proposed. It is time to apply stem cell studies, which is a field of expertise in regenerative medicine, to cancer treatment. Cancer treatments that effectively attack cancer stem cells acting as a manufacturing plant for producing differentiated cancer progenies will be designed by revealing the cancer stem cell system. Therefore, in the near future we hope that revolution will occur in cancer therapy to eradicate cancer and prevent the recurrence thereof. In this review we discuss the current situation and problems of cancer stem cell research.
AB - The concept of a "cancer stem cell system" that continues to supply cancer component cells has been proposed. It is time to apply stem cell studies, which is a field of expertise in regenerative medicine, to cancer treatment. Cancer treatments that effectively attack cancer stem cells acting as a manufacturing plant for producing differentiated cancer progenies will be designed by revealing the cancer stem cell system. Therefore, in the near future we hope that revolution will occur in cancer therapy to eradicate cancer and prevent the recurrence thereof. In this review we discuss the current situation and problems of cancer stem cell research.
KW - Cancer stem cell
KW - Cancer therapy
KW - Niche
KW - Stem cell
UR - http://www.scopus.com/inward/record.url?scp=42249086632&partnerID=8YFLogxK
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U2 - 10.3727/000000008783906982
DO - 10.3727/000000008783906982
M3 - Article
C2 - 18468231
AN - SCOPUS:42249086632
SN - 0963-6897
VL - 17
SP - 19
EP - 25
JO - Cell Transplantation
JF - Cell Transplantation
IS - 1-2
ER -